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Preferential targeting of somatic hypermutation to hotspot motifs and hypermutable sites and generation of mutational clusters in the IgVH alleles of a rheumatoid factor producing lymphoblastoid cell line.
Laskov R, Yahud V, Hamo R, Steinitz M. Laskov R, et al. Mol Immunol. 2011 Feb;48(5):733-45. doi: 10.1016/j.molimm.2010.10.009. Epub 2010 Dec 30. Mol Immunol. 2011. PMID: 21194753
Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
Chezar I, Lobel-Lavi L, Steinitz M, Laskov R. Chezar I, et al. Among authors: laskov r. Mol Immunol. 2008 Nov;46(1):80-90. doi: 10.1016/j.molimm.2008.07.002. Epub 2008 Aug 20. Mol Immunol. 2008. PMID: 18718665
Somatic mutations and activation-induced cytidine deaminase (AID) expression in established rheumatoid factor-producing lymphoblastoid cell line.
Gil Y, Levy-Nabot S, Steinitz M, Laskov R. Gil Y, et al. Among authors: laskov r. Mol Immunol. 2007 Jan;44(4):494-505. doi: 10.1016/j.molimm.2006.02.012. Epub 2006 Mar 30. Mol Immunol. 2007. PMID: 16574227
Somatic mutations in the Ig variable region genes and expression of novel Cmu-germline transcripts in a B-lymphoma cell line ("Farage") not producing Ig polypeptide chains.
Hochberg M, Gabay C, Laskov R. Hochberg M, et al. Among authors: laskov r. Leuk Lymphoma. 1998 Aug;30(5-6):637-49. doi: 10.3109/10428199809057576. Leuk Lymphoma. 1998. PMID: 9711926
Molecular characterization of an unusual non-Hodgkin's B-lymphoma cell line ("Farage") lacking the ability to produce immunoglobulin polypeptide chains.
Baruch M, Hochberg M, Gabay C, Ben-Bassat H, Shlomai Z, Laskov R. Baruch M, et al. Leuk Lymphoma. 1996 May;21(5-6):485-95. doi: 10.3109/10428199609093448. Leuk Lymphoma. 1996. PMID: 9172815
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