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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Among authors: latek rr. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862 Free article.
The SANT domain: a unique histone-tail-binding module?
Boyer LA, Latek RR, Peterson CL. Boyer LA, et al. Among authors: latek rr. Nat Rev Mol Cell Biol. 2004 Feb;5(2):158-63. doi: 10.1038/nrm1314. Nat Rev Mol Cell Biol. 2004. PMID: 15040448 Review. No abstract available.
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: latek rr. Mol Cell. 2003 Apr;11(4):895-904. doi: 10.1016/s1097-2765(03)00114-x. Mol Cell. 2003. PMID: 12718876 Free article.
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: latek rr. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925
siRNA Selection Server: an automated siRNA oligonucleotide prediction server.
Yuan B, Latek R, Hossbach M, Tuschl T, Lewitter F. Yuan B, et al. Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W130-4. doi: 10.1093/nar/gkh366. Nucleic Acids Res. 2004. PMID: 15215365 Free PMC article.
The transcription factor Eyes absent is a protein tyrosine phosphatase.
Tootle TL, Silver SJ, Davies EL, Newman V, Latek RR, Mills IA, Selengut JD, Parlikar BE, Rebay I. Tootle TL, et al. Among authors: latek rr. Nature. 2003 Nov 20;426(6964):299-302. doi: 10.1038/nature02097. Nature. 2003. PMID: 14628053
An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity.
Xiao Z, Latek R, Lodish HF. Xiao Z, et al. Oncogene. 2003 Feb 20;22(7):1057-69. doi: 10.1038/sj.onc.1206212. Oncogene. 2003. PMID: 12592392
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.
Azam M, Latek RR, Daley GQ. Azam M, et al. Among authors: latek rr. Cell. 2003 Mar 21;112(6):831-43. doi: 10.1016/s0092-8674(03)00190-9. Cell. 2003. PMID: 12654249 Free article.
Mechanisms and consequences of peptide selection by the I-Ak class II molecule.
Latek RR, Unanue ER. Latek RR, et al. Immunol Rev. 1999 Dec;172:209-28. doi: 10.1111/j.1600-065x.1999.tb01367.x. Immunol Rev. 1999. PMID: 10631948 Review.
Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules.
Latek RR, Petzold SJ, Unanue ER. Latek RR, et al. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11460-5. doi: 10.1073/pnas.210384197. Proc Natl Acad Sci U S A. 2000. PMID: 11016975 Free PMC article.
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