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Proteomic technology and its biomedical applications.
Lau AT, He QY, Chiu JF. Lau AT, et al. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Nov;35(11):965-75. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003. PMID: 14614532 Review.
A proteome analysis of the arsenite response in cultured lung cells: evidence for in vitro oxidative stress-induced apoptosis.
Lau AT, He QY, Chiu JF. Lau AT, et al. Biochem J. 2004 Sep 1;382(Pt 2):641-50. doi: 10.1042/BJ20040224. Biochem J. 2004. PMID: 15175009 Free PMC article.
However, the cellular response at the molecular level has not been studied extensively. In the present study, we provide for the first time a proteomic analysis of rat LECs (lung epithelial cells) treated with arsenite, with the aim of identifying defence proteins, probabl …
However, the cellular response at the molecular level has not been studied extensively. In the present study, we provide for the firs …
Proteomic and biochemical analyses of in vitro carcinogen-induced lung cell transformation: synergism between arsenic and benzo[a]pyrene.
Lau AT, Chiu JF. Lau AT, et al. Proteomics. 2006 Mar;6(5):1619-30. doi: 10.1002/pmic.200500332. Proteomics. 2006. PMID: 16456883
However, little is known about their effects exerted at the proteome level. Our previous study in rat lung epithelial cells showed that cell transformation frequency increased by more than 100-fold when arsenic was given in combination with B[a]P than cells either exposed …
However, little is known about their effects exerted at the proteome level. Our previous study in rat lung epithelial cells showed th …
Biomarkers of lung-related diseases: current knowledge by proteomic approaches.
Lau AT, Chiu JF. Lau AT, et al. J Cell Physiol. 2009 Dec;221(3):535-43. doi: 10.1002/jcp.21893. J Cell Physiol. 2009. PMID: 19681054 Free PMC article. Review.
The recent advancement of proteomics has made it possible to investigate the cellular response at a global level. In this review, the potential applications of proteomic approach in studying lung-related diseases and biomarker discovery will be discussed....
The recent advancement of proteomics has made it possible to investigate the cellular response at a global level. In this review, the …
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