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Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life.
Hines EP, White SS, Stanko JP, Gibbs-Flournoy EA, Lau C, Fenton SE. Hines EP, et al. Among authors: Lau C. Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105. doi: 10.1016/j.mce.2009.02.021. Epub 2009 Mar 9. Mol Cell Endocrinol. 2009. PMID: 19433254
The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.
Beggs KM, McGreal SR, McCarthy A, Gunewardena S, Lampe JN, Lau C, Apte U. Beggs KM, et al. Among authors: Lau C. Toxicol Appl Pharmacol. 2016 Aug 1;304:18-29. doi: 10.1016/j.taap.2016.05.001. Epub 2016 May 3. Toxicol Appl Pharmacol. 2016. PMID: 27153767 Free PMC article.
Perfluorinated compounds.
Lau C. Lau C. Exp Suppl. 2012;101:47-86. doi: 10.1007/978-3-7643-8340-4_3. Exp Suppl. 2012. PMID: 22945566 Review.
Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.
Abbott BD, Wolf CJ, Schmid JE, Das KP, Zehr RD, Helfant L, Nakayama S, Lindstrom AB, Strynar MJ, Lau C. Abbott BD, et al. Among authors: Lau C. Toxicol Sci. 2007 Aug;98(2):571-81. doi: 10.1093/toxsci/kfm110. Epub 2007 May 7. Toxicol Sci. 2007. PMID: 17488742
Effects of perfluorooctanoic acid exposure during pregnancy in the mouse.
Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM, Lindstrom AB, Strynar MJ. Lau C, et al. Toxicol Sci. 2006 Apr;90(2):510-8. doi: 10.1093/toxsci/kfj105. Epub 2006 Jan 16. Toxicol Sci. 2006. PMID: 16415327
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