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The CCN family of angiogenic regulators: the integrin connection.
Lau LF, Lam SC. Lau LF, et al. Exp Cell Res. 1999 Apr 10;248(1):44-57. doi: 10.1006/excr.1999.4456. Exp Cell Res. 1999. PMID: 10094812 Review. No abstract available.
The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling.
Chintala H, Krupska I, Yan L, Lau L, Grant M, Chaqour B. Chintala H, et al. Among authors: lau l. Development. 2015 Jul 1;142(13):2364-74. doi: 10.1242/dev.121913. Epub 2015 May 22. Development. 2015. PMID: 26002917 Free PMC article.
Report on the 8th international workshop on the CCN family of genes - Nice November 3-8, 2015.
Perbal B, Lau L, Lyons K, Kubota S, Yeger H, Fisher G. Perbal B, et al. Among authors: lau l. J Cell Commun Signal. 2016 Mar;10(1):77-86. doi: 10.1007/s12079-016-0317-y. Epub 2016 Feb 26. J Cell Commun Signal. 2016. PMID: 26920000 Free PMC article. No abstract available.
Report on the 9th international workshop on the CCN family of genes, November 2-7, 2017, Saint-Malo, France.
Yeger H, Brigstock D, Fisher G, Lau L, Leask A, Perbal B. Yeger H, et al. Among authors: lau l. J Cell Commun Signal. 2018 Sep;12(3):505-511. doi: 10.1007/s12079-018-0472-4. J Cell Commun Signal. 2018. PMID: 29926396 Free PMC article. No abstract available.
Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines.
Chen CC, Lau LF. Chen CC, et al. Among authors: lau lf. J Cell Commun Signal. 2010 Mar;4(1):63-9. doi: 10.1007/s12079-009-0080-4. Epub 2009 Nov 7. J Cell Commun Signal. 2010. PMID: 19898959 Free PMC article.
Construction and Analysis of an Allelic Series of Ccn1 Knockin Mice.
Monzon RI, Kim KH, Lau LF. Monzon RI, et al. Among authors: lau lf. Methods Mol Biol. 2017;1489:361-376. doi: 10.1007/978-1-4939-6430-7_30. Methods Mol Biol. 2017. PMID: 27734389
CYR61 (CCN1) is essential for placental development and vascular integrity.
Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC, Lau LF. Mo FE, et al. Among authors: lau lf. Mol Cell Biol. 2002 Dec;22(24):8709-20. doi: 10.1128/mcb.22.24.8709-8720.2002. Mol Cell Biol. 2002. PMID: 12446788 Free PMC article.
Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing.
Lin CG, Chen CC, Leu SJ, Grzeszkiewicz TM, Lau LF. Lin CG, et al. Among authors: lau lf. J Biol Chem. 2005 Mar 4;280(9):8229-37. doi: 10.1074/jbc.M404903200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611078
., and Lau, L. F. (2003) J. Biol. Chem. 278, 24200-24208). In this study, we show that CCN3 is highly expressed in granulation tissue of cutaneous wounds 5-7 days after injury and is capable of inducing responses in primary fibroblasts consistent with wound healing. ...
., and Lau, L. F. (2003) J. Biol. Chem. 278, 24200-24208). In this study, we show that CCN3 is highly expressed in granulation tissue …
Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo.
Juric V, Chen CC, Lau LF. Juric V, et al. Among authors: lau lf. Mol Cell Biol. 2009 Jun;29(12):3266-79. doi: 10.1128/MCB.00064-09. Epub 2009 Apr 13. Mol Cell Biol. 2009. PMID: 19364818 Free PMC article.
Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis.
Franzen CA, Chen CC, Todorović V, Juric V, Monzon RI, Lau LF. Franzen CA, et al. Among authors: lau lf. Mol Cancer Res. 2009 Jul;7(7):1045-55. doi: 10.1158/1541-7786.MCR-09-0017. Epub 2009 Jul 7. Mol Cancer Res. 2009. PMID: 19584265 Free PMC article.
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