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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model.
Rector RS, Thyfault JP, Uptergrove GM, Morris EM, Naples SP, Borengasser SJ, Mikus CR, Laye MJ, Laughlin MH, Booth FW, Ibdah JA. Rector RS, et al. Among authors: laughlin mh. J Hepatol. 2010 May;52(5):727-36. doi: 10.1016/j.jhep.2009.11.030. Epub 2010 Mar 4. J Hepatol. 2010. PMID: 20347174 Free PMC article.
Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats.
Rector RS, Uptergrove GM, Borengasser SJ, Mikus CR, Morris EM, Naples SP, Laye MJ, Laughlin MH, Booth FW, Ibdah JA, Thyfault JP. Rector RS, et al. Among authors: laughlin mh. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1179-87. doi: 10.1152/ajpendo.00703.2009. Epub 2010 Mar 16. Am J Physiol Endocrinol Metab. 2010. PMID: 20233940 Free PMC article.
Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats.
Linden MA, Lopez KT, Fletcher JA, Morris EM, Meers GM, Siddique S, Laughlin MH, Sowers JR, Thyfault JP, Ibdah JA, Rector RS. Linden MA, et al. Among authors: laughlin mh. Appl Physiol Nutr Metab. 2015 Oct;40(10):1038-47. doi: 10.1139/apnm-2015-0236. Epub 2015 Jun 24. Appl Physiol Nutr Metab. 2015. PMID: 26394261 Free PMC article.
Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats.
Linden MA, Meers GM, Ruebel ML, Jenkins NT, Booth FW, Laughlin MH, Ibdah JA, Thyfault JP, Rector RS. Linden MA, et al. Among authors: laughlin mh. Am J Physiol Regul Integr Comp Physiol. 2013 May 1;304(9):R763-71. doi: 10.1152/ajpregu.00537.2012. Epub 2013 Mar 6. Am J Physiol Regul Integr Comp Physiol. 2013. PMID: 23467323 Free PMC article.
Adipose tissue and vascular phenotypic modulation by voluntary physical activity and dietary restriction in obese insulin-resistant OLETF rats.
Crissey JM, Jenkins NT, Lansford KA, Thorne PK, Bayless DS, Vieira-Potter VJ, Rector RS, Thyfault JP, Laughlin MH, Padilla J. Crissey JM, et al. Among authors: laughlin mh. Am J Physiol Regul Integr Comp Physiol. 2014 Apr 15;306(8):R596-606. doi: 10.1152/ajpregu.00493.2013. Epub 2014 Feb 12. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 24523340 Free PMC article.
342 results