Laurent GJ - Search Results

1

Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land?

Jenkins RG, McAnulty RJ, Hart SL, Laurent GJ. Jenkins RG, et al. Among authors: laurent gj. Monaldi Arch Chest Dis. 2003 Jan-Mar;59(1):17-24. Monaldi Arch Chest Dis. 2003. PMID: 14533278 Review.

2

An integrin-targeted non-viral vector for pulmonary gene therapy.

Jenkins RG, Herrick SE, Meng QH, Kinnon C, Laurent GJ, McAnulty RJ, Hart SL. Jenkins RG, et al. Among authors: laurent gj. Gene Ther. 2000 Mar;7(5):393-400. doi: 10.1038/sj.gt.3301095. Gene Ther. 2000. PMID: 10694821

3

Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo.

Jenkins RG, Meng QH, Hodges RJ, Lee LK, Bottoms SE, Laurent GJ, Willis D, Ayazi Shamlou P, McAnulty RJ, Hart SL. Jenkins RG, et al. Among authors: laurent gj. Gene Ther. 2003 Jun;10(12):1026-34. doi: 10.1038/sj.gt.3301963. Gene Ther. 2003. PMID: 12776160

4

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

Hodges RJ, Jenkins RG, Wheeler-Jones CP, Copeman DM, Bottoms SE, Bellingan GJ, Nanthakumar CB, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Hodges RJ, et al. Among authors: laurent gj. Am J Pathol. 2004 Nov;165(5):1663-76. doi: 10.1016/S0002-9440(10)63423-2. Am J Pathol. 2004. PMID: 15509536 Free PMC article.

5

Escape from the matrix: multiple mechanisms for fibroblast activation in pulmonary fibrosis.

Laurent GJ, McAnulty RJ, Hill M, Chambers R. Laurent GJ, et al. Proc Am Thorac Soc. 2008 Apr 15;5(3):311-5. doi: 10.1513/pats.200710-159DR. Proc Am Thorac Soc. 2008. PMID: 18403325 Free PMC article.

6

Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.

Jenkins G, Hart SL, Hodges RJ, Meng QH, Kinnon C, Laurent GJ, McAnulty RJ. Jenkins G, et al. Among authors: laurent gj. Chest. 2002 Mar;121(3 Suppl):102S-104S. doi: 10.1378/chest.121.3_suppl.102s. Chest. 2002. PMID: 11893724 No abstract available.

7

The pathogenesis of pulmonary fibrosis: is there a fibrosis gene?

Marshall RP, McAnulty RJ, Laurent GJ. Marshall RP, et al. Among authors: laurent gj. Int J Biochem Cell Biol. 1997 Jan;29(1):107-20. doi: 10.1016/s1357-2725(96)00141-0. Int J Biochem Cell Biol. 1997. PMID: 9076945 Review.

8

Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor.

Marshall RP, McAnulty RJ, Laurent GJ. Marshall RP, et al. Among authors: laurent gj. Am J Respir Crit Care Med. 2000 Jun;161(6):1999-2004. doi: 10.1164/ajrccm.161.6.9907004. Am J Respir Crit Care Med. 2000. PMID: 10852780

9

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice.

Keerthisingam CB, Jenkins RG, Harrison NK, Hernandez-Rodriguez NA, Booth H, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Keerthisingam CB, et al. Among authors: laurent gj. Am J Pathol. 2001 Apr;158(4):1411-22. doi: 10.1016/s0002-9440(10)64092-8. Am J Pathol. 2001. PMID: 11290559 Free PMC article.

10

Increased endothelin-1 and its localization during the development of bleomycin-induced pulmonary fibrosis in rats.

Mutsaers SE, Foster ML, Chambers RC, Laurent GJ, McAnulty RJ. Mutsaers SE, et al. Among authors: laurent gj. Am J Respir Cell Mol Biol. 1998 May;18(5):611-9. doi: 10.1165/ajrcmb.18.5.2898. Am J Respir Cell Mol Biol. 1998. PMID: 9569231

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