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Mitophagy in neurodegeneration and aging.
Fivenson EM, Lautrup S, Sun N, Scheibye-Knudsen M, Stevnsner T, Nilsen H, Bohr VA, Fang EF. Fivenson EM, et al. Among authors: lautrup s. Neurochem Int. 2017 Oct;109:202-209. doi: 10.1016/j.neuint.2017.02.007. Epub 2017 Feb 21. Neurochem Int. 2017. PMID: 28235551 Free PMC article. Review.
NAD+ in Aging: Molecular Mechanisms and Translational Implications.
Fang EF, Lautrup S, Hou Y, Demarest TG, Croteau DL, Mattson MP, Bohr VA. Fang EF, et al. Among authors: lautrup s. Trends Mol Med. 2017 Oct;23(10):899-916. doi: 10.1016/j.molmed.2017.08.001. Epub 2017 Sep 9. Trends Mol Med. 2017. PMID: 28899755 Free PMC article. Review.
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA. Fang EF, et al. Among authors: lautrup s. Nat Neurosci. 2019 Mar;22(3):401-412. doi: 10.1038/s41593-018-0332-9. Epub 2019 Feb 11. Nat Neurosci. 2019. PMID: 30742114 Free PMC article.
Mitophagy and Neuroprotection.
Lou G, Palikaras K, Lautrup S, Scheibye-Knudsen M, Tavernarakis N, Fang EF. Lou G, et al. Among authors: lautrup s. Trends Mol Med. 2020 Jan;26(1):8-20. doi: 10.1016/j.molmed.2019.07.002. Epub 2019 Jul 30. Trends Mol Med. 2020. PMID: 31375365 Review.
NAD+ in Brain Aging and Neurodegenerative Disorders.
Lautrup S, Sinclair DA, Mattson MP, Fang EF. Lautrup S, et al. Cell Metab. 2019 Oct 1;30(4):630-655. doi: 10.1016/j.cmet.2019.09.001. Cell Metab. 2019. PMID: 31577933 Free PMC article. Review.
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA. Fang EF, et al. Among authors: lautrup s. Nat Commun. 2019 Nov 21;10(1):5284. doi: 10.1038/s41467-019-13172-8. Nat Commun. 2019. PMID: 31754102 Free PMC article.
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing.
Gilmour BC, Gudmundsrud R, Frank J, Hov A, Lautrup S, Aman Y, Røsjø H, Brenner C, Ziegler M, Tysnes OB, Tzoulis C, Omland T, Søraas A, Holmøy T, Bergersen LH, Storm-Mathisen J, Nilsen H, Fang EF. Gilmour BC, et al. Among authors: lautrup s. Mech Ageing Dev. 2020 Mar;186:111208. doi: 10.1016/j.mad.2020.111208. Epub 2020 Jan 15. Mech Ageing Dev. 2020. PMID: 31953124 Free article. Review.
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