Lautwein A - Search Results

1

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity.

Gideon P, John J, Frech M, Lautwein A, Clark R, Scheffler JE, Wittinghofer A. Gideon P, et al. Among authors: lautwein a. Mol Cell Biol. 1992 May;12(5):2050-6. doi: 10.1128/mcb.12.5.2050-2056.1992. Mol Cell Biol. 1992. PMID: 1569940 Free PMC article.

2

The inhibition of the GTPase activating protein-Ha-ras interaction by acidic lipids is due to physical association of the C-terminal domain of the GTPase activating protein with micellar structures.

Serth J, Lautwein A, Frech M, Wittinghofer A, Pingoud A. Serth J, et al. Among authors: lautwein a. EMBO J. 1991 Jun;10(6):1325-30. doi: 10.1002/j.1460-2075.1991.tb07651.x. EMBO J. 1991. PMID: 2026138 Free PMC article.

3

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.

Scheffzek K, Lautwein A, Kabsch W, Ahmadian MR, Wittinghofer A. Scheffzek K, et al. Among authors: lautwein a. Nature. 1996 Dec 12;384(6609):591-6. doi: 10.1038/384591a0. Nature. 1996. PMID: 8955277

4

Is there a rate-limiting step before GTP cleavage by H-ras p21?

Rensland H, Lautwein A, Wittinghofer A, Goody RS. Rensland H, et al. Among authors: lautwein a. Biochemistry. 1991 Nov 19;30(46):11181-5. doi: 10.1021/bi00110a023. Biochemistry. 1991. PMID: 1932038

5

Three-dimensional structure and properties of wild-type and mutant H-ras-encoded p21.

Wittinghofer A, Franken SM, Scheidig AJ, Rensland H, Lautwein A, Pai EF, Goody RS. Wittinghofer A, et al. Among authors: lautwein a. Ciba Found Symp. 1993;176:6-21; discussion 21-7. doi: 10.1002/9780470514450.ch2. Ciba Found Symp. 1993. PMID: 8299426 Review.

6

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin.

Ahmadian MR, Wiesmüller L, Lautwein A, Bischoff FR, Wittinghofer A. Ahmadian MR, et al. Among authors: lautwein a. J Biol Chem. 1996 Jul 5;271(27):16409-15. doi: 10.1074/jbc.271.27.16409. J Biol Chem. 1996. PMID: 8663212 Free article.

7

Crystallization and preliminary X-ray crystallographic study of the Ras-GTPase-activating domain of human p120GAP.

Scheffzek K, Lautwein A, Scherer A, Franken S, Wittinghofer A. Scheffzek K, et al. Among authors: lautwein a. Proteins. 1997 Feb;27(2):315-8. doi: 10.1002/(sici)1097-0134(199702)27:2<315::aid-prot17>3.0.co;2-p. Proteins. 1997. PMID: 9061795

8

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.

Scheffzek K, Ahmadian MR, Kabsch W, Wiesmüller L, Lautwein A, Schmitz F, Wittinghofer A. Scheffzek K, et al. Among authors: lautwein a. Science. 1997 Jul 18;277(5324):333-8. doi: 10.1126/science.277.5324.333. Science. 1997. PMID: 9219684

9

Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.

Scheidig AJ, Sanchez-Llorente A, Lautwein A, Pai EF, Corrie JE, Reid GP, Wittinghofer A, Goody RS. Scheidig AJ, et al. Among authors: lautwein a. Acta Crystallogr D Biol Crystallogr. 1994 Jul 1;50(Pt 4):512-20. doi: 10.1107/S090744499301443X. Acta Crystallogr D Biol Crystallogr. 1994. PMID: 15299412

10

Crystallization and preliminary X-ray structure analysis of thermally unstable p21(H-ras) guanosine complexes.

Scheffzek K, Kabsch W, Schlichting I, Pai EF, Lautwein A, Frech M, Wittinghoffer A, Goody RS. Scheffzek K, et al. Among authors: lautwein a. Acta Crystallogr D Biol Crystallogr. 1994 Jul 1;50(Pt 4):521-6. doi: 10.1107/S0907444994001253. Acta Crystallogr D Biol Crystallogr. 1994. PMID: 15299413

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