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Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.
Beaumont V, Zhong S, Lin H, Xu W, Bradaia A, Steidl E, Gleyzes M, Wadel K, Buisson B, Padovan-Neto FE, Chakroborty S, Ward KM, Harms JF, Beltran J, Kwan M, Ghavami A, Häggkvist J, Tóth M, Halldin C, Varrone A, Schaab C, Dybowski JN, Elschenbroich S, Lehtimäki K, Heikkinen T, Park L, Rosinski J, Mrzljak L, Lavery D, West AR, Schmidt CJ, Zaleska MM, Munoz-Sanjuan I. Beaumont V, et al. Among authors: lavery d. Neuron. 2016 Dec 21;92(6):1220-1237. doi: 10.1016/j.neuron.2016.10.064. Epub 2016 Dec 1. Neuron. 2016. PMID: 27916455 Free article.
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.
Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, Ross CA. Ratovitski T, et al. J Proteome Res. 2017 Aug 4;16(8):2692-2708. doi: 10.1021/acs.jproteome.6b00991. Epub 2017 Jul 3. J Proteome Res. 2017. PMID: 28653853 Free PMC article.
Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, Kwak S, Botas J, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. Langfelder P, et al. Among authors: lavery dj. Nat Neurosci. 2016 Apr;19(4):623-33. doi: 10.1038/nn.4256. Epub 2016 Feb 22. Nat Neurosci. 2016. PMID: 26900923 Free PMC article.
Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13.
Cariulo C, Verani M, Martufi P, Ingenito R, Finotto M, Deguire SM, Lavery DJ, Toledo-Sherman L, Lee R, Doherty EM, Vogt TF, Dominguez C, Lashuel HA, Petricca L, Caricasole A. Cariulo C, et al. Biochem Biophys Res Commun. 2020 Jan 15;521(3):549-554. doi: 10.1016/j.bbrc.2019.09.097. Epub 2019 Oct 31. Biochem Biophys Res Commun. 2020. PMID: 31677786
Adenovirus E1A and E1B genes are regulated posttranscriptionally in human lymphoid cells.
Lavery DJ, Chen-Kiang S. Lavery DJ, et al. J Virol. 1990 Nov;64(11):5349-59. doi: 10.1128/JVI.64.11.5349-5359.1990. J Virol. 1990. PMID: 2145444 Free PMC article.
Taken together, these results suggested that repression and altered expression of E1A and E1B genes may provide a molecular basis of delayed kinetics of infection of lymphoid cells with adenovirus (D. Lavery, S. M. Fu, T. Lufkin, and S. Chen-Kiang, J. Virol. 61:1466 …
Taken together, these results suggested that repression and altered expression of E1A and E1B genes may provide a molecular basis of delayed …
114 results