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Mini-review: Foldosome regulation of androgen receptor action in prostate cancer.
Cano LQ, Lavery DN, Bevan CL. Cano LQ, et al. Among authors: lavery dn. Mol Cell Endocrinol. 2013 Apr 30;369(1-2):52-62. doi: 10.1016/j.mce.2013.01.023. Epub 2013 Feb 8. Mol Cell Endocrinol. 2013. PMID: 23395916 Review.
Negative regulation of the androgen receptor gene through a primate-specific androgen response element present in the 5' UTR.
Hay CW, Watt K, Hunter I, Lavery DN, MacKenzie A, McEwan IJ. Hay CW, et al. Among authors: lavery dn. Horm Cancer. 2014 Oct;5(5):299-311. doi: 10.1007/s12672-014-0185-y. Epub 2014 Jun 4. Horm Cancer. 2014. PMID: 24895212 Free PMC article.
Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a.
Lavery DN, McEwan IJ. Lavery DN, et al. Biochemistry. 2008 Mar 18;47(11):3352-9. doi: 10.1021/bi702220p. Epub 2008 Feb 20. Biochemistry. 2008. PMID: 18284209
Structural characterization of the native NH2-terminal transactivation domain of the human androgen receptor: a collapsed disordered conformation underlies structural plasticity and protein-induced folding.
Lavery DN, McEwan IJ. Lavery DN, et al. Biochemistry. 2008 Mar 18;47(11):3360-9. doi: 10.1021/bi702221e. Epub 2008 Feb 20. Biochemistry. 2008. PMID: 18284208
The co-chaperone p23 promotes prostate cancer motility and metastasis.
Cano LQ, Lavery DN, Sin S, Spanjaard E, Brooke GN, Tilman JD, Abroaf A, Gaughan L, Robson CN, Heer R, Mauri F, de Rooij J, Driouch K, Bevan CL. Cano LQ, et al. Among authors: lavery dn. Mol Oncol. 2015 Jan;9(1):295-308. doi: 10.1016/j.molonc.2014.08.014. Epub 2014 Sep 6. Mol Oncol. 2015. PMID: 25241147 Free PMC article.
Engineered repressors are potent inhibitors of androgen receptor activity.
Brooke GN, Powell SM, Lavery DN, Waxman J, Buluwela L, Ali S, Bevan CL. Brooke GN, et al. Among authors: lavery dn. Oncotarget. 2014 Feb 28;5(4):959-69. doi: 10.18632/oncotarget.1360. Oncotarget. 2014. PMID: 24659630 Free PMC article.
Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer.
Reebye V, Querol Cano L, Lavery DN, Brooke GN, Powell SM, Chotai D, Walker MM, Whitaker HC, Wait R, Hurst HC, Bevan CL. Reebye V, et al. Among authors: lavery dn. Mol Endocrinol. 2012 Oct;26(10):1694-706. doi: 10.1210/me.2012-1056. Epub 2012 Aug 16. Mol Endocrinol. 2012. PMID: 22899854 Free PMC article.
Androgen receptor signalling in prostate cancer: the functional consequences of acetylation.
Lavery DN, Bevan CL. Lavery DN, et al. J Biomed Biotechnol. 2011;2011:862125. doi: 10.1155/2011/862125. Epub 2010 Dec 28. J Biomed Biotechnol. 2011. PMID: 21274273 Free PMC article.
Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors.
Lavery DN, Villaronga MA, Walker MM, Patel A, Belandia B, Bevan CL. Lavery DN, et al. J Biol Chem. 2011 May 20;286(20):17796-808. doi: 10.1074/jbc.M110.198655. Epub 2011 Mar 17. J Biol Chem. 2011. PMID: 21454491 Free PMC article.
The human androgen receptor AF1 transactivation domain: interactions with transcription factor IIF and molten-globule-like structural characteristics.
Lavery DN, McEwan IJ. Lavery DN, et al. Biochem Soc Trans. 2006 Dec;34(Pt 6):1054-7. doi: 10.1042/BST0341054. Biochem Soc Trans. 2006. PMID: 17073749
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