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Melatonin--the key to the gate of sleep.
Shochat T, Haimov I, Lavie P. Shochat T, et al. Ann Med. 1998 Feb;30(1):109-14. doi: 10.3109/07853899808999392. Ann Med. 1998. PMID: 9556097
Bax/Mcl-1 balance affects neutrophil survival in intermittent hypoxia and obstructive sleep apnea: effects of p38MAPK and ERK1/2 signaling.
Dyugovskaya L, Polyakov A, Cohen-Kaplan V, Lavie P, Lavie L. Dyugovskaya L, et al. J Transl Med. 2012 Oct 22;10:211. doi: 10.1186/1479-5876-10-211. J Transl Med. 2012. PMID: 23088735 Free PMC article.
Similar to neutrophils of healthy subjects exposed to IH (0.97± 0.2), in OSA neutrophils, Bax/Mcl-1 ratio was significantly lower compared to normoxic controls (1.0±0.5 vs.1.99±0.3, p=0.015), and Bax did not co-localize with mitochondria. ...
Similar to neutrophils of healthy subjects exposed to IH (0.97± 0.2), in OSA neutrophils, Bax/Mcl-1 ratio was significantly lower compared t …
Melatonin administration alters semen quality in healthy men.
Luboshitzky R, Shen-Orr Z, Nave R, Lavi S, Lavie P. Luboshitzky R, et al. J Androl. 2002 Jul-Aug;23(4):572-8. J Androl. 2002. PMID: 12065466 Clinical Trial.
Smoking interacts with sleep apnea to increase cardiovascular risk.
Lavie L, Lavie P. Lavie L, et al. Sleep Med. 2008 Mar;9(3):247-53. doi: 10.1016/j.sleep.2007.03.018. Epub 2007 May 21. Sleep Med. 2008. PMID: 17513169
The effects of 1-year treatment with a herbst mandibular advancement splint on obstructive sleep apnea, oxidative stress, and endothelial function.
Itzhaki S, Dorchin H, Clark G, Lavie L, Lavie P, Pillar G. Itzhaki S, et al. Chest. 2007 Mar;131(3):740-749. doi: 10.1378/chest.06-0965. Chest. 2007. PMID: 17356088 Clinical Trial.

The mean EF improved significantly from 1.77 +/- 0.4 before treatment to 2.1 +/- 0.4 after 3 months of treatment (p < 0.05) and 2.0 +/- 0.3 after 1 year of treatment (p = 0.055), which were similar to the values of the reference group. Thiobarbituric acid-reactiv

The mean EF improved significantly from 1.77 +/- 0.4 before treatment to 2.1 +/- 0.4 after 3 months of treatment (p < 0.05) and 2.

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