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Increased sensitivity of rheumatoid synoviocytes to Schnurri-3 expression in TNF-α and IL-17A induced osteoblastic differentiation.
Lavocat F, Osta B, Miossec P. Lavocat F, et al. Bone. 2016 Jun;87:89-96. doi: 10.1016/j.bone.2016.04.008. Epub 2016 Apr 9. Bone. 2016. PMID: 27072520
Interleukin-25 Produced by Synoviocytes Has Anti-inflammatory Effects by Acting As a Receptor Antagonist for Interleukin-17A Function.
Lavocat F, Ndongo-Thiam N, Miossec P. Lavocat F, et al. Front Immunol. 2017 May 31;8:647. doi: 10.3389/fimmu.2017.00647. eCollection 2017. Front Immunol. 2017. PMID: 28620392 Free PMC article.
Protective effect of low dose intra-articular cadmium on inflammation and joint destruction in arthritis.
Bonaventura P, Courbon G, Lamboux A, Lavocat F, Marotte H, Albarède F, Miossec P. Bonaventura P, et al. Among authors: lavocat f. Sci Rep. 2017 May 25;7(1):2415. doi: 10.1038/s41598-017-02611-5. Sci Rep. 2017. PMID: 28546541 Free PMC article.
T-cell clones from Th1, Th17 or Th1/17 lineages and their signature cytokines have different capacity to activate endothelial cells or synoviocytes.
Lavocat F, Maggi L, Annunziato F, Miossec P. Lavocat F, et al. Cytokine. 2016 Dec;88:241-250. doi: 10.1016/j.cyto.2016.09.019. Epub 2016 Sep 28. Cytokine. 2016. PMID: 27693917
IL-17A and TNF-α Increase the Expression of the Antiapoptotic Adhesion Molecule Amigo-2 in Arthritis Synoviocytes.
Benedetti G, Bonaventura P, Lavocat F, Miossec P. Benedetti G, et al. Among authors: lavocat f. Front Immunol. 2016 Jun 27;7:254. doi: 10.3389/fimmu.2016.00254. eCollection 2016. Front Immunol. 2016. PMID: 27446084 Free PMC article.
Blockade of bone morphogenetic protein signaling potentiates the pro-inflammatory phenotype induced by interleukin-17 and tumor necrosis factor-α combination in rheumatoid synoviocytes.
Varas A, Valencia J, Lavocat F, Martínez VG, Thiam NN, Hidalgo L, Fernández-Sevilla LM, Sacedón R, Vicente A, Miossec P. Varas A, et al. Among authors: lavocat f. Arthritis Res Ther. 2015 Jul 28;17(1):192. doi: 10.1186/s13075-015-0710-6. Arthritis Res Ther. 2015. PMID: 26215036 Free PMC article.
Differential Effects of IL-17A and TNF-α on Osteoblastic Differentiation of Isolated Synoviocytes and on Bone Explants from Arthritis Patients.
Osta B, Roux JP, Lavocat F, Pierre M, Ndongo-Thiam N, Boivin G, Miossec P. Osta B, et al. Among authors: lavocat f. Front Immunol. 2015 Apr 7;6:151. doi: 10.3389/fimmu.2015.00151. eCollection 2015. Front Immunol. 2015. PMID: 25904914 Free PMC article.
Effects of Interleukin-17A on Osteogenic Differentiation of Isolated Human Mesenchymal Stem Cells.
Osta B, Lavocat F, Eljaafari A, Miossec P. Osta B, et al. Among authors: lavocat f. Front Immunol. 2014 Sep 2;5:425. doi: 10.3389/fimmu.2014.00425. eCollection 2014. Front Immunol. 2014. PMID: 25228904 Free PMC article.
Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: contribution to the chronicity of rheumatoid arthritis.
Eljaafari A, Tartelin ML, Aissaoui H, Chevrel G, Osta B, Lavocat F, Miossec P. Eljaafari A, et al. Among authors: lavocat f. Arthritis Rheum. 2012 Jul;64(7):2147-57. doi: 10.1002/art.34391. Arthritis Rheum. 2012. PMID: 22275154
Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells.
Hot A, Lavocat F, Lenief V, Miossec P. Hot A, et al. Among authors: lavocat f. Ann Rheum Dis. 2013 May;72(5):754-60. doi: 10.1136/annrheumdis-2012-201887. Epub 2012 Aug 21. Ann Rheum Dis. 2013. PMID: 22915623
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