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Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression.
Lawal HO, Terrell A, Lam HA, Djapri C, Jang J, Hadi R, Roberts L, Shahi V, Chou MT, Biedermann T, Huang B, Lawless GM, Maidment NT, Krantz DE. Lawal HO, et al. Among authors: lawless gm. Mol Psychiatry. 2014 Feb;19(2):235-42. doi: 10.1038/mp.2012.170. Epub 2012 Dec 11. Mol Psychiatry. 2014. PMID: 23229049 Free PMC article.
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration.
Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH, Jackson GR. Karsten SL, et al. Neuron. 2006 Sep 7;51(5):549-60. doi: 10.1016/j.neuron.2006.07.019. Neuron. 2006. PMID: 16950154 Free article.
Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial.
Baloh RH, Johnson JP, Avalos P, Allred P, Svendsen S, Gowing G, Roxas K, Wu A, Donahue B, Osborne S, Lawless G, Shelley B, Wheeler K, Prina C, Fine D, Kendra-Romito T, Stokes H, Manoukian V, Muthukumaran A, Garcia L, Bañuelos MG, Godoy M, Bresee C, Yu H, Drazin D, Ross L, Naruse R, Babu H, Macklin EA, Vo A, Elsayegh A, Tourtellotte W, Maya M, Burford M, Diaz F, Patil CG, Lewis RA, Svendsen CN. Baloh RH, et al. Among authors: lawless g. Nat Med. 2022 Sep;28(9):1813-1822. doi: 10.1038/s41591-022-01956-3. Epub 2022 Sep 5. Nat Med. 2022. PMID: 36064599 Free PMC article. Clinical Trial.
50 results