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Caspase-8: not so silently deadly.
Feltham R, Vince JE, Lawlor KE. Feltham R, et al. Among authors: lawlor ke. Clin Transl Immunology. 2017 Jan 6;6(1):e124. doi: 10.1038/cti.2016.83. eCollection 2017 Jan. Clin Transl Immunology. 2017. PMID: 28197335 Free PMC article. Review.
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J. Rickard JA, et al. Among authors: lawlor ke. Cell. 2014 May 22;157(5):1175-88. doi: 10.1016/j.cell.2014.04.019. Epub 2014 May 8. Cell. 2014. PMID: 24813849
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
Allam R, Lawlor KE, Yu EC, Mildenhall AL, Moujalled DM, Lewis RS, Ke F, Mason KD, White MJ, Stacey KJ, Strasser A, O'Reilly LA, Alexander W, Kile BT, Vaux DL, Vince JE. Allam R, et al. Among authors: ke f, lawlor ke. EMBO Rep. 2014 Sep;15(9):982-90. doi: 10.15252/embr.201438463. Epub 2014 Jul 2. EMBO Rep. 2014. PMID: 24990442 Free PMC article.
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.
Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J. Rickard JA, et al. Among authors: lawlor ke. Elife. 2014 Dec 2;3:e03464. doi: 10.7554/eLife.03464. Elife. 2014. PMID: 25443632 Free PMC article.
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