Lawrence DA - Search Results

1

PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.

Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH. Osterholzer JJ, et al. Among authors: lawrence da. J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992. Epub 2012 Jun 6. J Pathol. 2012. PMID: 22262246 Free PMC article.

2

The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.

Courey AJ, Horowitz JC, Kim KK, Koh TJ, Novak ML, Subbotina N, Warnock M, Xue B, Cunningham AK, Lin Y, Goldklang MP, Simon RH, Lawrence DA, Sisson TH. Courey AJ, et al. Among authors: lawrence da. Blood. 2011 Aug 25;118(8):2313-21. doi: 10.1182/blood-2010-12-324574. Epub 2011 Jul 6. Blood. 2011. PMID: 21734232 Free PMC article.

3

Vitronectin-binding PAI-1 protects against the development of cardiac fibrosis through interaction with fibroblasts.

Zhong J, Yang HC, Kon V, Fogo AB, Lawrence DA, Ma J. Zhong J, et al. Among authors: lawrence da. Lab Invest. 2014 Jun;94(6):633-44. doi: 10.1038/labinvest.2014.51. Epub 2014 Mar 31. Lab Invest. 2014. PMID: 24687120 Free PMC article.

4

Plasminogen Activator Inhibitor-1 Reduces Tissue-Type Plasminogen Activator-Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose.

Pant A, Kopec AK, Baker KS, Cline-Fedewa H, Lawrence DA, Luyendyk JP. Pant A, et al. Among authors: lawrence da. Am J Pathol. 2018 May;188(5):1204-1212. doi: 10.1016/j.ajpath.2018.01.010. Epub 2018 Feb 16. Am J Pathol. 2018. PMID: 29454747 Free PMC article.

5

Defibrotide Therapy for SARS-CoV-2 ARDS.

Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Frame D, et al. Among authors: lawrence da. Chest. 2022 Aug;162(2):346-355. doi: 10.1016/j.chest.2022.03.046. Epub 2022 Apr 9. Chest. 2022. PMID: 35413279 Free PMC article. Clinical Trial.

6

Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha.

Liao H, Hyman MC, Lawrence DA, Pinsky DJ. Liao H, et al. Among authors: lawrence da. FASEB J. 2007 Mar;21(3):935-49. doi: 10.1096/fj.06-6285com. Epub 2006 Dec 28. FASEB J. 2007. PMID: 17197388 Free article.

7

Structure-function relationships of plasminogen activator inhibitor-1 and its potential as a therapeutic agent.

Cale JM, Lawrence DA. Cale JM, et al. Among authors: lawrence da. Curr Drug Targets. 2007 Sep;8(9):971-81. doi: 10.2174/138945007781662337. Curr Drug Targets. 2007. PMID: 17896949 Review.

8

Novel bis-arylsulfonamides and aryl sulfonimides as inactivators of plasminogen activator inhibitor-1 (PAI-1).

El-Ayache NC, Li SH, Warnock M, Lawrence DA, Emal CD. El-Ayache NC, et al. Among authors: lawrence da. Bioorg Med Chem Lett. 2010 Feb 1;20(3):966-70. doi: 10.1016/j.bmcl.2009.12.051. Epub 2009 Dec 21. Bioorg Med Chem Lett. 2010. PMID: 20056540 Free PMC article.

9

Characterization of a novel class of polyphenolic inhibitors of plasminogen activator inhibitor-1.

Cale JM, Li SH, Warnock M, Su EJ, North PR, Sanders KL, Puscau MM, Emal CD, Lawrence DA. Cale JM, et al. Among authors: lawrence da. J Biol Chem. 2010 Mar 12;285(11):7892-902. doi: 10.1074/jbc.M109.067967. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061381 Free PMC article.

10

Development of inhibitors of plasminogen activator inhibitor-1.

Li SH, Lawrence DA. Li SH, et al. Among authors: lawrence da. Methods Enzymol. 2011;501:177-207. doi: 10.1016/B978-0-12-385950-1.00009-2. Methods Enzymol. 2011. PMID: 22078535

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