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32 results
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Joint modelling of confounding factors and prominent genetic regulators provides increased accuracy in genetical genomics studies.
Fusi N, Stegle O, Lawrence ND. Fusi N, et al. Among authors: lawrence nd. PLoS Comput Biol. 2012 Jan;8(1):e1002330. doi: 10.1371/journal.pcbi.1002330. Epub 2012 Jan 5. PLoS Comput Biol. 2012. PMID: 22241974 Free PMC article.
Inference of RNA polymerase II transcription dynamics from chromatin immunoprecipitation time course data.
wa Maina C, Honkela A, Matarese F, Grote K, Stunnenberg HG, Reid G, Lawrence ND, Rattray M. wa Maina C, et al. Among authors: lawrence nd. PLoS Comput Biol. 2014 May 15;10(5):e1003598. doi: 10.1371/journal.pcbi.1003598. eCollection 2014 May. PLoS Comput Biol. 2014. PMID: 24830797 Free PMC article.
Efficient inference for sparse latent variable models of transcriptional regulation.
Dai Z, Iqbal M, Lawrence ND, Rattray M. Dai Z, et al. Among authors: lawrence nd. Bioinformatics. 2017 Dec 1;33(23):3776-3783. doi: 10.1093/bioinformatics/btx508. Bioinformatics. 2017. PMID: 28961802 Free PMC article.
Modeling meiotic chromosomes indicates a size dependent contribution of telomere clustering and chromosome rigidity to homologue juxtaposition.
Penfold CA, Brown PE, Lawrence ND, Goldman AS. Penfold CA, et al. Among authors: lawrence nd. PLoS Comput Biol. 2012;8(5):e1002496. doi: 10.1371/journal.pcbi.1002496. Epub 2012 May 3. PLoS Comput Biol. 2012. PMID: 22570605 Free PMC article.
Hierarchical Bayesian modelling of gene expression time series across irregularly sampled replicates and clusters.
Hensman J, Lawrence ND, Rattray M. Hensman J, et al. Among authors: lawrence nd. BMC Bioinformatics. 2013 Aug 20;14:252. doi: 10.1186/1471-2105-14-252. BMC Bioinformatics. 2013. PMID: 23962281 Free PMC article.
Detecting regulatory gene-environment interactions with unmeasured environmental factors.
Fusi N, Lippert C, Borgwardt K, Lawrence ND, Stegle O. Fusi N, et al. Among authors: lawrence nd. Bioinformatics. 2013 Jun 1;29(11):1382-9. doi: 10.1093/bioinformatics/btt148. Epub 2013 Apr 4. Bioinformatics. 2013. PMID: 23559640
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities.
Sanguinetti G, Lawrence ND, Rattray M. Sanguinetti G, et al. Among authors: lawrence nd. Bioinformatics. 2006 Nov 15;22(22):2775-81. doi: 10.1093/bioinformatics/btl473. Epub 2006 Sep 11. Bioinformatics. 2006. PMID: 16966362
Probe-level measurement error improves accuracy in detecting differential gene expression.
Liu X, Milo M, Lawrence ND, Rattray M. Liu X, et al. Among authors: lawrence nd. Bioinformatics. 2006 Sep 1;22(17):2107-13. doi: 10.1093/bioinformatics/btl361. Epub 2006 Jul 4. Bioinformatics. 2006. PMID: 16820429
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription.
Sanguinetti G, Rattray M, Lawrence ND. Sanguinetti G, et al. Among authors: lawrence nd. Bioinformatics. 2006 Jul 15;22(14):1753-9. doi: 10.1093/bioinformatics/btl154. Epub 2006 Apr 21. Bioinformatics. 2006. PMID: 16632490
Accounting for probe-level noise in principal component analysis of microarray data.
Sanguinetti G, Milo M, Rattray M, Lawrence ND. Sanguinetti G, et al. Among authors: lawrence nd. Bioinformatics. 2005 Oct 1;21(19):3748-54. doi: 10.1093/bioinformatics/bti617. Epub 2005 Aug 9. Bioinformatics. 2005. PMID: 16091409
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