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Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients.
McKenzie M, Lazarou M, Thorburn DR, Ryan MT. McKenzie M, et al. Among authors: lazarou m. J Mol Biol. 2006 Aug 18;361(3):462-9. doi: 10.1016/j.jmb.2006.06.057. Epub 2006 Jul 5. J Mol Biol. 2006. PMID: 16857210
Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller.
Webb CT, Gorman MA, Lazarou M, Ryan MT, Gulbis JM. Webb CT, et al. Among authors: lazarou m. Mol Cell. 2006 Jan 6;21(1):123-33. doi: 10.1016/j.molcel.2005.11.010. Mol Cell. 2006. PMID: 16387659
Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis.
McKenzie M, Lazarou M, Thorburn DR, Ryan MT. McKenzie M, et al. Among authors: lazarou m. Anal Biochem. 2007 May 15;364(2):128-37. doi: 10.1016/j.ab.2007.02.022. Epub 2007 Feb 24. Anal Biochem. 2007. PMID: 17391635
Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I.
Lazarou M, McKenzie M, Ohtake A, Thorburn DR, Ryan MT. Lazarou M, et al. Mol Cell Biol. 2007 Jun;27(12):4228-37. doi: 10.1128/MCB.00074-07. Epub 2007 Apr 16. Mol Cell Biol. 2007. PMID: 17438127 Free PMC article.
Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease.
Dunning CJ, McKenzie M, Sugiana C, Lazarou M, Silke J, Connelly A, Fletcher JM, Kirby DM, Thorburn DR, Ryan MT. Dunning CJ, et al. Among authors: lazarou m. EMBO J. 2007 Jul 11;26(13):3227-37. doi: 10.1038/sj.emboj.7601748. Epub 2007 Jun 7. EMBO J. 2007. PMID: 17557076 Free PMC article.
Assembly of mitochondrial complex I and defects in disease.
Lazarou M, Thorburn DR, Ryan MT, McKenzie M. Lazarou M, et al. Biochim Biophys Acta. 2009 Jan;1793(1):78-88. doi: 10.1016/j.bbamcr.2008.04.015. Epub 2008 May 4. Biochim Biophys Acta. 2009. PMID: 18501715 Review.
Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits.
McKenzie M, Lazarou M, Ryan MT. McKenzie M, et al. Among authors: lazarou m. Methods Enzymol. 2009;456:321-39. doi: 10.1016/S0076-6879(08)04418-2. Methods Enzymol. 2009. PMID: 19348897
Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria.
Lazarou M, Smith SM, Thorburn DR, Ryan MT, McKenzie M. Lazarou M, et al. FEBS J. 2009 Nov;276(22):6701-13. doi: 10.1111/j.1742-4658.2009.07384.x. Epub 2009 Oct 16. FEBS J. 2009. PMID: 19843159
Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.
Lazarou M, Stojanovski D, Frazier AE, Kotevski A, Dewson G, Craigen WJ, Kluck RM, Vaux DL, Ryan MT. Lazarou M, et al. J Biol Chem. 2010 Nov 19;285(47):36876-83. doi: 10.1074/jbc.M110.159301. Epub 2010 Sep 17. J Biol Chem. 2010. PMID: 20851889 Free PMC article.
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ. Jin SM, et al. Among authors: lazarou m. J Cell Biol. 2010 Nov 29;191(5):933-42. doi: 10.1083/jcb.201008084. J Cell Biol. 2010. PMID: 21115803 Free PMC article.
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