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Structure, function, and regulation of mitofusin-2 in health and disease.
Chandhok G, Lazarou M, Neumann B. Chandhok G, et al. Biol Rev Camb Philos Soc. 2018 May;93(2):933-949. doi: 10.1111/brv.12378. Epub 2017 Oct 25. Biol Rev Camb Philos Soc. 2018. PMID: 29068134 Free PMC article. Review.
Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease.
Dunning CJ, McKenzie M, Sugiana C, Lazarou M, Silke J, Connelly A, Fletcher JM, Kirby DM, Thorburn DR, Ryan MT. Dunning CJ, et al. EMBO J. 2007 Jul 11;26(13):3227-37. doi: 10.1038/sj.emboj.7601748. Epub 2007 Jun 7. EMBO J. 2007. PMID: 17557076 Free PMC article.
Assembly of mitochondrial complex I and defects in disease.
Lazarou M, Thorburn DR, Ryan MT, McKenzie M. Lazarou M, et al. Biochim Biophys Acta. 2009 Jan;1793(1):78-88. doi: 10.1016/j.bbamcr.2008.04.015. Epub 2008 May 4. Biochim Biophys Acta. 2009. PMID: 18501715 Review.
Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria.
Lazarou M, Smith SM, Thorburn DR, Ryan MT, McKenzie M. Lazarou M, et al. FEBS J. 2009 Nov;276(22):6701-13. doi: 10.1111/j.1742-4658.2009.07384.x. Epub 2009 Oct 16. FEBS J. 2009. PMID: 19843159
Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.
Lazarou M, Stojanovski D, Frazier AE, Kotevski A, Dewson G, Craigen WJ, Kluck RM, Vaux DL, Ryan MT. Lazarou M, et al. J Biol Chem. 2010 Nov 19;285(47):36876-83. doi: 10.1074/jbc.M110.159301. Epub 2010 Sep 17. J Biol Chem. 2010. PMID: 20851889 Free PMC article.
Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1.
McKenzie M, Tucker EJ, Compton AG, Lazarou M, George C, Thorburn DR, Ryan MT. McKenzie M, et al. J Mol Biol. 2011 Dec 2;414(3):413-26. doi: 10.1016/j.jmb.2011.10.012. Epub 2011 Oct 14. J Mol Biol. 2011. PMID: 22019594
Keeping the immune system in check: a role for mitophagy.
Lazarou M. Lazarou M. Immunol Cell Biol. 2015 Jan;93(1):3-10. doi: 10.1038/icb.2014.75. Epub 2014 Sep 30. Immunol Cell Biol. 2015. PMID: 25267485 Review.
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