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Age-dependent alterations of human recombinant GM-CSF effects on human granulocytes.
Seres I, Csongor J, Mohácsi A, Leövey A, Fülöp T. Seres I, et al. Mech Ageing Dev. 1993 Oct 1;71(1-2):143-54. doi: 10.1016/0047-6374(93)90042-p. Mech Ageing Dev. 1993. PMID: 8309279
By the use of Pertussis toxin and H7 it was demonstrated that a different signal transduction pathway in neutrophils of elderly subjects is activated by GM-CSF or FMLP if compared to that of young subjects. ...
By the use of Pertussis toxin and H7 it was demonstrated that a different signal transduction pathway in neutrophils of elderly subje …
Age related variations of some polymorphonuclear leukocyte functions.
Fülöp T Jr, Fóris G, Wórum I, Paragh G, Leövey A. Fülöp T Jr, et al. Mech Ageing Dev. 1985 Jan;29(1):1-8. doi: 10.1016/0047-6374(85)90041-7. Mech Ageing Dev. 1985. PMID: 3845309
Therefore, it was concluded that the aging of PMNLs is partly a sex related process. The intensive release of both beta-glucuronidase (beta-G) and ELP by the PMNLs of aged subjects after in vitro treatment with calcium ionophore A23187, Cytochalasin B or low density lipopr …
Therefore, it was concluded that the aging of PMNLs is partly a sex related process. The intensive release of both beta-glucuronidase …
Age-dependent changes of the Fc gamma-receptor-mediated functions of human monocytes.
Fülöp T, Fóris G, Wórum I, Leövey A. Fülöp T, et al. Int Arch Allergy Appl Immunol. 1984;74(1):76-9. doi: 10.1159/000233520. Int Arch Allergy Appl Immunol. 1984. PMID: 6231251
The phagocytosis increased significantly with aging in both sexes, whereas a decrease in ADCC activity was found....
The phagocytosis increased significantly with aging in both sexes, whereas a decrease in ADCC activity was found....
The immunosuppressive effect of methimazole on cell-mediated immunity is mediated by its capacity to inhibit peroxidase and to scavenge free oxygen radicals.
Balazs C, Kiss E, Leövey A, Farid NR. Balazs C, et al. Clin Endocrinol (Oxf). 1986 Jul;25(1):7-16. doi: 10.1111/j.1365-2265.1986.tb03590.x. Clin Endocrinol (Oxf). 1986. PMID: 3024872
A concentration of 10(-4) M MMI inhibited the immediate rise in intracellular cAMP triggered by PHA and the subsequent time dependent decrement over 24 h. The drug (10(-3) M) also exerted a significant inhibitory effect on antibody-dependent cell-mediated cytotoxici
A concentration of 10(-4) M MMI inhibited the immediate rise in intracellular cAMP triggered by PHA and the subsequent time dependent
Immunomodulating effect of low density lipoprotein on human monocytes.
Paragh G, Nagy JT, Szondy E, Fóris G, Leövey A. Paragh G, et al. Clin Exp Immunol. 1986 Jun;64(3):665-72. Clin Exp Immunol. 1986. PMID: 3024882 Free PMC article.
On the other hand, LDL diminished markedly the Fc gamma receptor (Fc gamma R) mediated rosette formation, phagocytosis and the antibody dependent cellular cytotoxicity (ADCC) of monocytes without a significant decrease in the IgG binding capability of cells. High levels of …
On the other hand, LDL diminished markedly the Fc gamma receptor (Fc gamma R) mediated rosette formation, phagocytosis and the antibody depe …
Age-related changes in cAMP and cGMP levels during phagocytosis in human polymorphonuclear leukocytes.
Fülöp T, Fóris G, Leövey A. Fülöp T, et al. Mech Ageing Dev. 1984 Oct 15;27(2):233-7. doi: 10.1016/0047-6374(84)90048-4. Mech Ageing Dev. 1984. PMID: 6092792
In PMNLs obtained from healthy young males the cAMP level rose to a maximal value during the first 15 min and returned to the starting level at the 60th min of phagocytosis. ...
In PMNLs obtained from healthy young males the cAMP level rose to a maximal value during the first 15 min and returned to the startin …
Antibody-dependent cell-mediated cytotoxicity in Graves disease.
Balázs C, Leövey A, Szerze P, Kovács L, Bordán L. Balázs C, et al. Acta Med Acad Sci Hung. 1977;34(4):235-9. Acta Med Acad Sci Hung. 1977. PMID: 581819
Alterations of the FMLP-induced Ca2+ efflux from human monocytes with aging.
Fülöp T Jr, Hauck M, Wórum I, Fóris G, Leövey A. Fülöp T Jr, et al. Immunol Lett. 1987 Apr;14(4):283-6. doi: 10.1016/0165-2478(87)90005-8. Immunol Lett. 1987. PMID: 3583321
The Ca2+ with the calmodulin system plays a major role in the receptor-induced intracellular biochemical events. Thus, as in our previous studies, we found an altered postreceptorial coupling in the case of elderly, we were interested to elucidate the Ca2+ transport in the …
The Ca2+ with the calmodulin system plays a major role in the receptor-induced intracellular biochemical events. Thus, as in our prev …
Investigation of the chemiluminescence associated with phagocytic and intracellular killing activity of human polymorphonuclear leucocytes and monocytes.
Szerze P, Balázs C, Csongor J, Nagy J, Leövey A. Szerze P, et al. Haematologia (Budap). 1978-1979;12(1-4):199-207. Haematologia (Budap). 1978. PMID: 94028
A significant, opsonization-dependent increase in photon emission of polymorphonuclear leucocytes and monocytes was observed induced by engulfment of opsonized, heat-killed and living fungi (Saccharomyces cerevisiae), aggregated gamma globulin, latex and India ink particle
A significant, opsonization-dependent increase in photon emission of polymorphonuclear leucocytes and monocytes was observed induced
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