Le Hir H - Search Results

1

The protein Mago provides a link between splicing and mRNA localization.

Le Hir H, Gatfield D, Braun IC, Forler D, Izaurralde E. Le Hir H, et al. EMBO Rep. 2001 Dec;2(12):1119-24. doi: 10.1093/embo-reports/kve245. Epub 2001 Nov 21. EMBO Rep. 2001. PMID: 11743026 Free PMC article.

2

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.

Le Hir H, Izaurralde E, Maquat LE, Moore MJ. Le Hir H, et al. EMBO J. 2000 Dec 15;19(24):6860-9. doi: 10.1093/emboj/19.24.6860. EMBO J. 2000. PMID: 11118221 Free PMC article.

3

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.

Le Hir H, Gatfield D, Izaurralde E, Moore MJ. Le Hir H, et al. EMBO J. 2001 Sep 3;20(17):4987-97. doi: 10.1093/emboj/20.17.4987. EMBO J. 2001. PMID: 11532962 Free PMC article.

4

The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila.

Gatfield D, Le Hir H, Schmitt C, Braun IC, Köcher T, Wilm M, Izaurralde E. Gatfield D, et al. Among authors: le hir h. Curr Biol. 2001 Oct 30;11(21):1716-21. doi: 10.1016/s0960-9822(01)00532-2. Curr Biol. 2001. PMID: 11696332 Free article.

5

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly.

Reichert VL, Le Hir H, Jurica MS, Moore MJ. Reichert VL, et al. Among authors: le hir h. Genes Dev. 2002 Nov 1;16(21):2778-91. doi: 10.1101/gad.1030602. Genes Dev. 2002. PMID: 12414731 Free PMC article.

6

Splicing enhances translation in mammalian cells: an additional function of the exon junction complex.

Nott A, Le Hir H, Moore MJ. Nott A, et al. Among authors: le hir h. Genes Dev. 2004 Jan 15;18(2):210-22. doi: 10.1101/gad.1163204. Genes Dev. 2004. PMID: 14752011 Free PMC article.

7

How introns influence and enhance eukaryotic gene expression.

Le Hir H, Nott A, Moore MJ. Le Hir H, et al. Trends Biochem Sci. 2003 Apr;28(4):215-20. doi: 10.1016/S0968-0004(03)00052-5. Trends Biochem Sci. 2003. PMID: 12713906 Review.

8

Exon Junction Complexes can have distinct functional flavours to regulate specific splicing events.

Wang Z, Ballut L, Barbosa I, Le Hir H. Wang Z, et al. Among authors: le hir h. Sci Rep. 2018 Jun 22;8(1):9509. doi: 10.1038/s41598-018-27826-y. Sci Rep. 2018. PMID: 29934576 Free PMC article.

9

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions.

Le Hir H, Moore MJ, Maquat LE. Le Hir H, et al. Genes Dev. 2000 May 1;14(9):1098-108. Genes Dev. 2000. PMID: 10809668 Free PMC article.

10

A UPF3-mediated regulatory switch that maintains RNA surveillance.

Chan WK, Bhalla AD, Le Hir H, Nguyen LS, Huang L, Gécz J, Wilkinson MF. Chan WK, et al. Among authors: le hir h. Nat Struct Mol Biol. 2009 Jul;16(7):747-53. doi: 10.1038/nsmb.1612. Epub 2009 Jun 7. Nat Struct Mol Biol. 2009. PMID: 19503078

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