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The scaffold protein menin is essential for activating the MYC locus and MYC-mediated androgen receptor transcription in androgen receptor-dependent prostate cancer cells.
Luo Y, Vlaeminck-Guillem V, Teinturier R, Abou Ziki R, Bertolino P, Le Romancer M, Zhang CX. Luo Y, et al. Among authors: le romancer m. Cancer Commun (Lond). 2021 Dec;41(12):1427-1430. doi: 10.1002/cac2.12217. Epub 2021 Dec 1. Cancer Commun (Lond). 2021. PMID: 34850609 Free PMC article. No abstract available.
Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway.
Teinturier R, Luo Y, Decaussin-Petrucci M, Vlaeminck-Guillem V, Vacherot F, Firlej V, Bonnavion R, Abou Ziki R, Gherardi S, Goddard I, Gadot N, Bertolino P, Le Romancer M, Zhang CX. Teinturier R, et al. Among authors: le romancer m. Oncogene. 2021 Feb;40(6):1118-1127. doi: 10.1038/s41388-020-01589-1. Epub 2020 Dec 15. Oncogene. 2021. PMID: 33323967
Non-genomic signaling of steroid receptors in cancer.
Thiebaut C, Vlaeminck-Guillem V, Trédan O, Poulard C, Le Romancer M. Thiebaut C, et al. Among authors: le romancer m. Mol Cell Endocrinol. 2021 Dec 1;538:111453. doi: 10.1016/j.mce.2021.111453. Epub 2021 Sep 11. Mol Cell Endocrinol. 2021. PMID: 34520815 Free article. Review.
Reduced menin expression leads to decreased ERα expression and is correlated with the occurrence of human luminal B-like and ER-negative breast cancer subtypes.
Teinturier R, Abou Ziki R, Kassem L, Luo Y, Malbeteau L, Gherardi S, Corbo L, Bertolino P, Bachelot T, Treilleux I, Zhang CX, Le Romancer M. Teinturier R, et al. Among authors: le romancer m. Breast Cancer Res Treat. 2021 Dec;190(3):389-401. doi: 10.1007/s10549-021-06339-9. Epub 2021 Sep 24. Breast Cancer Res Treat. 2021. PMID: 34561764 Free PMC article.
Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant.
Jacquemetton J, Kassem L, Poulard C, Dahmani A, De Plater L, Montaudon E, Sourd L, Morisset L, El Botty R, Chateau-Joubert S, Vacher S, Bièche I, Treilleux I, Trédan O, Marangoni E, Le Romancer M. Jacquemetton J, et al. Among authors: le romancer m. Breast Cancer Res. 2021 May 21;23(1):57. doi: 10.1186/s13058-021-01433-8. Breast Cancer Res. 2021. PMID: 34020697 Free PMC article.
Activation of rapid oestrogen signalling in aggressive human breast cancers.
Poulard C, Treilleux I, Lavergne E, Bouchekioua-Bouzaghou K, Goddard-Léon S, Chabaud S, Trédan O, Corbo L, Le Romancer M. Poulard C, et al. Among authors: le romancer m. EMBO Mol Med. 2012 Nov;4(11):1200-13. doi: 10.1002/emmm.201201615. Epub 2012 Oct 15. EMBO Mol Med. 2012. PMID: 23065768 Free PMC article.
LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.
Bouchekioua-Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, Bachelot T, Chabaud S, Mader S, Dayan G, Treilleux I, Corbo L, Le Romancer M. Bouchekioua-Bouzaghou K, et al. Among authors: le romancer m. Int J Cancer. 2014 Sep 15;135(6):1307-18. doi: 10.1002/ijc.28781. Epub 2014 Mar 4. Int J Cancer. 2014. PMID: 24615515 Free article.
89 results