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mTOR, translation initiation and cancer.
Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N. Mamane Y, et al. Among authors: lebacquer o. Oncogene. 2006 Oct 16;25(48):6416-22. doi: 10.1038/sj.onc.1209888. Oncogene. 2006. PMID: 17041626 Review.
p53-dependent translational control of senescence and transformation via 4E-BPs.
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, Shahbazian D, Livingstone M, Costa-Mattioli M, Teodoro JG, Sonenberg N. Petroulakis E, et al. Among authors: lebacquer o. Cancer Cell. 2009 Nov 6;16(5):439-46. doi: 10.1016/j.ccr.2009.09.025. Cancer Cell. 2009. PMID: 19878875 Free article.
[When translation arises from its TORpor].
Le Bacquer O, Martineau Y, Mamane Y. Le Bacquer O, et al. Med Sci (Paris). 2006 May;22(5):514-8. doi: 10.1051/medsci/2006225514. Med Sci (Paris). 2006. PMID: 16687120 Review. French.
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N. Le Bacquer O, et al. J Clin Invest. 2007 Feb;117(2):387-96. doi: 10.1172/JCI29528. J Clin Invest. 2007. PMID: 17273556 Free PMC article.
mTOR signaling: implications for cancer and anticancer therapy.
Petroulakis E, Mamane Y, Le Bacquer O, Shahbazian D, Sonenberg N. Petroulakis E, et al. Br J Cancer. 2007;96 Suppl:R11-5. Br J Cancer. 2007. PMID: 17393579
mTOR signaling: implications for cancer and anticancer therapy.
Petroulakis E, Mamane Y, Le Bacquer O, Shahbazian D, Sonenberg N. Petroulakis E, et al. Br J Cancer. 2006 Jan 30;94(2):195-9. doi: 10.1038/sj.bjc.6602902. Br J Cancer. 2006. PMID: 16404421 Free PMC article. Review.
Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity.
Le Bacquer O, Combe K, Montaurier C, Salles J, Giraudet C, Patrac V, Domingues-Faria C, Guillet C, Louche K, Boirie Y, Sonenberg N, Moro C, Walrand S. Le Bacquer O, et al. Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201700128. Epub 2017 Jul 3. Mol Nutr Food Res. 2017. PMID: 28544394
S6K1 plays a critical role in early adipocyte differentiation.
Carnevalli LS, Masuda K, Frigerio F, Le Bacquer O, Um SH, Gandin V, Topisirovic I, Sonenberg N, Thomas G, Kozma SC. Carnevalli LS, et al. Dev Cell. 2010 May 18;18(5):763-74. doi: 10.1016/j.devcel.2010.02.018. Dev Cell. 2010. PMID: 20493810 Free PMC article.
mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F. Le Bacquer O, et al. J Endocrinol. 2013 Jan 2;216(1):21-9. doi: 10.1530/JOE-12-0351. Print 2013 Jan. J Endocrinol. 2013. PMID: 23092880
Inflammatory role of Toll-like receptors in human and murine adipose tissue.
Poulain-Godefroy O, Le Bacquer O, Plancq P, Lecoeur C, Pattou F, Fr├╝hbeck G, Froguel P. Poulain-Godefroy O, et al. Mediators Inflamm. 2010;2010:823486. doi: 10.1155/2010/823486. Epub 2010 Mar 22. Mediators Inflamm. 2010. PMID: 20339530 Free PMC article.
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