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NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Catley L, Weisberg E, Tai YT, Atadja P, Remiszewski S, Hideshima T, Mitsiades N, Shringarpure R, LeBlanc R, Chauhan D, Munshi NC, Schlossman R, Richardson P, Griffin J, Anderson KC. Catley L, et al. Among authors: leblanc r. Blood. 2003 Oct 1;102(7):2615-22. doi: 10.1182/blood-2003-01-0233. Epub 2003 Jun 19. Blood. 2003. PMID: 12816865 Free article.
2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells.
Chauhan D, Catley L, Hideshima T, Li G, Leblanc R, Gupta D, Sattler M, Richardson P, Schlossman RL, Podar K, Weller E, Munshi N, Anderson KC. Chauhan D, et al. Among authors: leblanc r. Blood. 2002 Sep 15;100(6):2187-94. doi: 10.1182/blood-2002-02-0376. Blood. 2002. PMID: 12200384 Free article.
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma.
Richardson PG, Schlossman RL, Weller E, Hideshima T, Mitsiades C, Davies F, LeBlanc R, Catley LP, Doss D, Kelly K, McKenney M, Mechlowicz J, Freeman A, Deocampo R, Rich R, Ryoo JJ, Chauhan D, Balinski K, Zeldis J, Anderson KC. Richardson PG, et al. Among authors: leblanc r. Blood. 2002 Nov 1;100(9):3063-7. doi: 10.1182/blood-2002-03-0996. Blood. 2002. PMID: 12384400 Free article. Clinical Trial.
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway.
LeBlanc R, Hideshima T, Catley LP, Shringarpure R, Burger R, Mitsiades N, Mitsiades C, Cheema P, Chauhan D, Richardson PG, Anderson KC, Munshi NC. LeBlanc R, et al. Blood. 2004 Mar 1;103(5):1787-90. doi: 10.1182/blood-2003-02-0361. Epub 2003 Sep 25. Blood. 2004. PMID: 14512311 Free article.
821 results