LeRoith D - Search Results

1

The role of the IGF system in cancer growth and metastasis: overview and recent insights.

Samani AA, Yakar S, LeRoith D, Brodt P. Samani AA, et al. Among authors: leroith d. Endocr Rev. 2007 Feb;28(1):20-47. doi: 10.1210/er.2006-0001. Epub 2006 Aug 24. Endocr Rev. 2007. PMID: 16931767 Review.

2

Clinical relevance of systemic and local IGF-I.

Yakar S, Pennisi P, Wu Y, Zhao H, LeRoith D. Yakar S, et al. Among authors: leroith d. Endocr Dev. 2005;9:11-16. doi: 10.1159/000085718. Endocr Dev. 2005. PMID: 15879684 Review.

3

The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: Lessons from animal models.

Yakar S, Leroith D, Brodt P. Yakar S, et al. Among authors: leroith d. Cytokine Growth Factor Rev. 2005 Aug-Oct;16(4-5):407-20. doi: 10.1016/j.cytogfr.2005.01.010. Cytokine Growth Factor Rev. 2005. PMID: 15886048 Review.

4

Liver-specific IGF-I gene deficient mice exhibit accelerated diabetes in response to streptozotocin, associated with early onset of insulin resistance.

Yu R, Yakar S, Liu YL, Lu Y, LeRoith D, Miao D, Liu JL. Yu R, et al. Among authors: leroith d. Mol Cell Endocrinol. 2003 Jun 30;204(1-2):31-42. doi: 10.1016/s0303-7207(03)00145-x. Mol Cell Endocrinol. 2003. PMID: 12850279

5

PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells.

Zhao H, Dupont J, Yakar S, Karas M, LeRoith D. Zhao H, et al. Among authors: leroith d. Oncogene. 2004 Jan 22;23(3):786-94. doi: 10.1038/sj.onc.1207162. Oncogene. 2004. PMID: 14737113

6

Circulating IGF-1 and its role in cancer: lessons from the IGF-1 gene deletion (LID) mouse.

Yakar S, Pennisi P, Zhao H, Zhang Y, LeRoith D. Yakar S, et al. Among authors: leroith d. Novartis Found Symp. 2004;262:3-9; discussion 9-18, 265-8. Novartis Found Symp. 2004. PMID: 15562820 Review.

7

The somatomedin hypothesis: 2001.

Le Roith D, Bondy C, Yakar S, Liu JL, Butler A. Le Roith D, et al. Endocr Rev. 2001 Feb;22(1):53-74. doi: 10.1210/edrv.22.1.0419. Endocr Rev. 2001. PMID: 11159816 Review.

8

Intact insulin and insulin-like growth factor-I receptor signaling is required for growth hormone effects on skeletal muscle growth and function in vivo.

Kim H, Barton E, Muja N, Yakar S, Pennisi P, Leroith D. Kim H, et al. Among authors: leroith d. Endocrinology. 2005 Apr;146(4):1772-9. doi: 10.1210/en.2004-0906. Epub 2004 Dec 23. Endocrinology. 2005. PMID: 15618350

9

TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival.

Toyoshima Y, Karas M, Yakar S, Dupont J, Lee Helman, LeRoith D. Toyoshima Y, et al. Among authors: leroith d. J Biol Chem. 2004 Jun 11;279(24):25898-904. doi: 10.1074/jbc.M400661200. Epub 2004 Mar 22. J Biol Chem. 2004. PMID: 15037619 Free article.

10

Role of growth hormone (GH) in liver regeneration.

Pennisi PA, Kopchick JJ, Thorgeirsson S, LeRoith D, Yakar S. Pennisi PA, et al. Among authors: leroith d. Endocrinology. 2004 Oct;145(10):4748-55. doi: 10.1210/en.2004-0655. Epub 2004 Jul 8. Endocrinology. 2004. PMID: 15242989

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