Lea SM - Search Results

1

Type 9 secretion system structures reveal a new protein transport mechanism.

Lauber F, Deme JC, Lea SM, Berks BC. Lauber F, et al. Among authors: lea sm. Nature. 2018 Dec;564(7734):77-82. doi: 10.1038/s41586-018-0693-y. Epub 2018 Nov 7. Nature. 2018. PMID: 30405243 Free PMC article.

2

TatBC, TatB, and TatC form structurally autonomous units within the twin arginine protein transport system of Escherichia coli.

Orriss GL, Tarry MJ, Ize B, Sargent F, Lea SM, Palmer T, Berks BC. Orriss GL, et al. Among authors: lea sm. FEBS Lett. 2007 Aug 21;581(21):4091-7. doi: 10.1016/j.febslet.2007.07.044. Epub 2007 Jul 30. FEBS Lett. 2007. PMID: 17686475 Free PMC article.

3

Structures of the Shigella flexneri type 3 secretion system protein MxiC reveal conformational variability amongst homologues.

Deane JE, Roversi P, King C, Johnson S, Lea SM. Deane JE, et al. Among authors: lea sm. J Mol Biol. 2008 Apr 4;377(4):985-92. doi: 10.1016/j.jmb.2008.01.072. Epub 2008 Feb 4. J Mol Biol. 2008. PMID: 18304577 Free PMC article.

4

Crystal structure of Spa40, the specificity switch for the Shigella flexneri type III secretion system.

Deane JE, Graham SC, Mitchell EP, Flot D, Johnson S, Lea SM. Deane JE, et al. Among authors: lea sm. Mol Microbiol. 2008 Jul;69(1):267-76. doi: 10.1111/j.1365-2958.2008.06293.x. Epub 2008 May 15. Mol Microbiol. 2008. PMID: 18485071 Free PMC article.

5

The Escherichia coli cell division protein and model Tat substrate SufI (FtsP) localizes to the septal ring and has a multicopper oxidase-like structure.

Tarry M, Arends SJ, Roversi P, Piette E, Sargent F, Berks BC, Weiss DS, Lea SM. Tarry M, et al. Among authors: lea sm. J Mol Biol. 2009 Feb 20;386(2):504-19. doi: 10.1016/j.jmb.2008.12.043. Epub 2008 Dec 25. J Mol Biol. 2009. PMID: 19135451 Free PMC article.

6

Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates.

Schneider MC, Prosser BE, Caesar JJ, Kugelberg E, Li S, Zhang Q, Quoraishi S, Lovett JE, Deane JE, Sim RB, Roversi P, Johnson S, Tang CM, Lea SM. Schneider MC, et al. Among authors: lea sm. Nature. 2009 Apr 16;458(7240):890-3. doi: 10.1038/nature07769. Epub 2009 Feb 18. Nature. 2009. PMID: 19225461 Free PMC article.

7

Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout.

Hodgkinson JL, Horsley A, Stabat D, Simon M, Johnson S, da Fonseca PC, Morris EP, Wall JS, Lea SM, Blocker AJ. Hodgkinson JL, et al. Among authors: lea sm. Nat Struct Mol Biol. 2009 May;16(5):477-85. doi: 10.1038/nsmb.1599. Epub 2009 Apr 26. Nat Struct Mol Biol. 2009. PMID: 19396171 Free PMC article.

8

Mechanism for the hydrolysis of a sulfur-sulfur bond based on the crystal structure of the thiosulfohydrolase SoxB.

Sauvé V, Roversi P, Leath KJ, Garman EF, Antrobus R, Lea SM, Berks BC. Sauvé V, et al. Among authors: lea sm. J Biol Chem. 2009 Aug 7;284(32):21707-18. doi: 10.1074/jbc.M109.002709. Epub 2009 Jun 16. J Biol Chem. 2009. PMID: 19535341 Free PMC article.

9

Structural analysis of substrate binding by the TatBC component of the twin-arginine protein transport system.

Tarry MJ, Schäfer E, Chen S, Buchanan G, Greene NP, Lea SM, Palmer T, Saibil HR, Berks BC. Tarry MJ, et al. Among authors: lea sm. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13284-9. doi: 10.1073/pnas.0901566106. Epub 2009 Jul 29. Proc Natl Acad Sci U S A. 2009. PMID: 19666509 Free PMC article.

10

Timing is everything: the regulation of type III secretion.

Deane JE, Abrusci P, Johnson S, Lea SM. Deane JE, et al. Among authors: lea sm. Cell Mol Life Sci. 2010 Apr;67(7):1065-75. doi: 10.1007/s00018-009-0230-0. Epub 2009 Dec 31. Cell Mol Life Sci. 2010. PMID: 20043184 Free PMC article. Review.

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