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Caspase-11 protects against bacteria that escape the vacuole.
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA. Aachoui Y, et al. Among authors: leaf ia. Science. 2013 Feb 22;339(6122):975-8. doi: 10.1126/science.1230751. Epub 2013 Jan 24. Science. 2013. PMID: 23348507 Free PMC article.
What can target kidney fibrosis?
Leaf IA, Duffield JS. Leaf IA, et al. Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i89-i97. doi: 10.1093/ndt/gfw388. Nephrol Dial Transplant. 2017. PMID: 28391346 Review.
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