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Ataluren (PTC124) induces cystic fibrosis transmembrane conductance regulator protein expression and activity in children with nonsense mutation cystic fibrosis.
Sermet-Gaudelus I, Boeck KD, Casimir GJ, Vermeulen F, Leal T, Mogenet A, Roussel D, Fritsch J, Hanssens L, Hirawat S, Miller NL, Constantine S, Reha A, Ajayi T, Elfring GL, Miller LL. Sermet-Gaudelus I, et al. Among authors: leal t. Am J Respir Crit Care Med. 2010 Nov 15;182(10):1262-72. doi: 10.1164/rccm.201001-0137OC. Epub 2010 Jul 9. Am J Respir Crit Care Med. 2010. PMID: 20622033 Clinical Trial.
Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency.
Sorio C, Montresor A, Bolomini-Vittori M, Caldrer S, Rossi B, Dusi S, Angiari S, Johansson JE, Vezzalini M, Leal T, Calcaterra E, Assael BM, Melotti P, Laudanna C. Sorio C, et al. Among authors: leal t. Am J Respir Crit Care Med. 2016 May 15;193(10):1123-33. doi: 10.1164/rccm.201510-1922OC. Am J Respir Crit Care Med. 2016. PMID: 26694899
CFTR biomarkers: time for promotion to surrogate end-point.
De Boeck K, Kent L, Davies J, Derichs N, Amaral M, Rowe SM, Middleton P, de Jonge H, Bronsveld I, Wilschanski M, Melotti P, Danner-Boucher I, Boerner S, Fajac I, Southern K, de Nooijer RA, Bot A, de Rijke Y, de Wachter E, Leal T, Vermeulen F, Hug MJ, Rault G, Nguyen-Khoa T, Barreto C, Proesmans M, Sermet-Gaudelus I; European Cystic Fibrosis Society Clinical Trial Network Standardisation Committee. De Boeck K, et al. Among authors: leal t. Eur Respir J. 2013 Jan;41(1):203-16. doi: 10.1183/09031936.00057512. Epub 2012 Aug 9. Eur Respir J. 2013. PMID: 22878883 Free article. Review.
Influence of perfusate temperature on nasal potential difference.
Bronsveld I, Vermeulen F, Sands D, Leal T, Leonard A, Melotti P, Yaakov Y, de Nooijer R, De Boeck K, Sermet I, Wilschanski M, Middleton PG; European Cystic Fibrosis Society – Diagnostic Network Working Group. Bronsveld I, et al. Among authors: leal t. Eur Respir J. 2013 Aug;42(2):389-93. doi: 10.1183/09031936.00097712. Epub 2012 Oct 25. Eur Respir J. 2013. PMID: 23100510 Free article.
Basic protocol for transepithelial nasal potential difference measurements.
Schüler D, Sermet-Gaudelus I, Wilschanski M, Ballmann M, Dechaux M, Edelman A, Hug M, Leal T, Lebacq J, Lebecque P, Lenoir G, Stanke F, Wallemacq P, Tümmler B, Knowles MR. Schüler D, et al. Among authors: leal t. J Cyst Fibros. 2004 Aug;3 Suppl 2:151-5. doi: 10.1016/j.jcf.2004.05.032. J Cyst Fibros. 2004. PMID: 15463949 Free article. Review.
335 results