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A model high surface area alumina-supported palladium catalyst.
Lear T, Marshall R, Gibson EK, Schütt T, Klapötke TM, Rupprechter G, Freund HJ, Winfield JM, Lennon D. Lear T, et al. Phys Chem Chem Phys. 2005 Feb 21;7(4):565-7. doi: 10.1039/b418708c. Phys Chem Chem Phys. 2005. PMID: 19787870
A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis.
Chen Y, Evankovich JW, Lear TB, Tuncer F, Kennerdell JR, Camarco DP, Shishido MS, Liu Y, Chen BB. Chen Y, et al. Among authors: Lear TB. Redox Biol. 2020 Mar 4;32:101485. doi: 10.1016/j.redox.2020.101485. Online ahead of print. Redox Biol. 2020. PMID: 32171724 Free PMC article.
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
Lear TB, Lockwood KC, Larsen M, Tuncer F, Kennerdell JR, Morse C, Valenzi E, Tabib T, Jurczak MJ, Kass DJ, Evankovich JW, Finkel T, Lafyatis R, Liu Y, Chen BB. Lear TB, et al. J Biol Chem. 2020 Mar 27;295(13):4171-4180. doi: 10.1074/jbc.AC119.012066. Epub 2020 Feb 17. J Biol Chem. 2020. PMID: 32071084
The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity.
Tong Y, Lear TB, Evankovich J, Chen Y, Londino JD, Myerburg MM, Zhang Y, Popescu ID, McDyer JF, McVerry BJ, Lockwood KC, Jurczak MJ, Liu Y, Chen BB. Tong Y, et al. Among authors: Lear TB. JCI Insight. 2020 Feb 13;5(3):e133652. doi: 10.1172/jci.insight.133652. JCI Insight. 2020. PMID: 31990690 Free PMC article.
KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.
Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB. Lear TB, et al. JCI Insight. 2019 Oct 3;4(19):e129110. doi: 10.1172/jci.insight.129110. JCI Insight. 2019. PMID: 31578312 Free PMC article.
Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs.
Evankovich J, Lear T, Baldwin C, Chen Y, White V, Villandre J, Londino J, Liu Y, McVerry B, Kitsios GD, Mallampalli RK, Chen BB. Evankovich J, et al. Among authors: Lear T. Am J Respir Cell Mol Biol. 2020 Feb;62(2):157-167. doi: 10.1165/rcmb.2018-0373OC. Am J Respir Cell Mol Biol. 2020. PMID: 31385713
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