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LecT-Hepa facilitates estimating treatment outcome during interferon therapy in chronic hepatitis C patients.
Zou X, Chi X, Pan Y, Du D, Sun H, Matsuda A, Li W, Kuno A, Zhang X, Narimatsu H, Niu J, Zhang Y. Zou X, et al. Clin Proteomics. 2014 Dec 11;11(1):44. doi: 10.1186/1559-0275-11-44. eCollection 2014. Clin Proteomics. 2014. PMID: 25593566 Free PMC article.
Here, we investigated the clinical utility of LecT-Hepa for evaluation of treatment outcome. RESULTS: Firstly, ninety-seven patients with CHC were used for comparison of LecT-Hepa in serum and plasma. ...We found that LecT-Hepa might refl …
Here, we investigated the clinical utility of LecT-Hepa for evaluation of treatment outcome. RESULTS: Firstly, ninety-seven pa …
LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients.
Ito K, Kuno A, Ikehara Y, Sugiyama M, Saito H, Aoki Y, Matsui T, Imamura M, Korenaga M, Murata K, Masaki N, Tanaka Y, Hige S, Izumi N, Kurosaki M, Nishiguchi S, Sakamoto M, Kage M, Narimatsu H, Mizokami M. Ito K, et al. Hepatology. 2012 Oct;56(4):1448-56. doi: 10.1002/hep.25815. Hepatology. 2012. PMID: 22535703
LecT-Hepa correlated well with the fibrosis stage as determined by liver biopsy. ...AUC scores of LecT-Hepa at each fibrosis stage were greater than those of the seven aforementioned noninvasive tests and markers. ...
LecT-Hepa correlated well with the fibrosis stage as determined by liver biopsy. ...AUC scores of LecT-Hepa at e
Comparison of LecT-Hepa and FibroScan for assessment of liver fibrosis in hepatitis B virus infected patients with different ALT levels.
Du D, Zhu X, Kuno A, Matsuda A, Tsuruno C, Yu D, Zhang Y, Ikehara Y, Tanaka Y, Zhang X, Narimatsu H. Du D, et al. Clin Chim Acta. 2012 Nov 12;413(21-22):1796-9. doi: 10.1016/j.cca.2012.07.005. Epub 2012 Jul 13. Clin Chim Acta. 2012. PMID: 22796373
We compared the reliability of LecT-Hepa with that of FibroScan for evaluation of liver fibrosis. METHODS: The effects of increased alanine aminotransferase (ALT) activities on LecT-Hepa and FibroScan were investigated. RESULTS: The areas under the rec …
We compared the reliability of LecT-Hepa with that of FibroScan for evaluation of liver fibrosis. METHODS: The effects of incr …
LecT-Hepa: A triplex lectin-antibody sandwich immunoassay for estimating the progression dynamics of liver fibrosis assisted by a bedside clinical chemistry analyzer and an automated pretreatment machine.
Kuno A, Ikehara Y, Tanaka Y, Saito K, Ito K, Tsuruno C, Nagai S, Takahama Y, Mizokami M, Hirabayashi J, Narimatsu H. Kuno A, et al. Clin Chim Acta. 2011 Sep 18;412(19-20):1767-72. doi: 10.1016/j.cca.2011.05.028. Epub 2011 May 30. Clin Chim Acta. 2011. PMID: 21645500
Two glyco-parameters obtained by HISCL showed a linear correlation with that from a reported assay (R>0.90). The formula for monitoring fibrosis (LecT-Hepa) was given by a combination of the glyco-parameters. This correlated with the fibrosis stage from biopsy (R …
Two glyco-parameters obtained by HISCL showed a linear correlation with that from a reported assay (R>0.90). The formula for monitoring f …