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Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells.
Shan D, Ledbetter JA, Press OW. Shan D, et al. Among authors: ledbetter ja. Cancer Immunol Immunother. 2000 Mar;48(12):673-83. doi: 10.1007/s002620050016. Cancer Immunol Immunother. 2000. PMID: 10752475
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.
Hellström I, Raycraft J, Hayden-Ledbetter M, Ledbetter JA, Schummer M, McIntosh M, Drescher C, Urban N, Hellström KE. Hellström I, et al. Among authors: ledbetter ja. Cancer Res. 2003 Jul 1;63(13):3695-700. Cancer Res. 2003. PMID: 12839961 Free article.
CD20-directed small modular immunopharmaceutical, TRU-015, depletes normal and malignant B cells.
Hayden-Ledbetter MS, Cerveny CG, Espling E, Brady WA, Grosmaire LS, Tan P, Bader R, Slater S, Nilsson CA, Barone DS, Simon A, Bradley C, Thompson PA, Wahl AF, Ledbetter JA. Hayden-Ledbetter MS, et al. Among authors: ledbetter ja. Clin Cancer Res. 2009 Apr 15;15(8):2739-46. doi: 10.1158/1078-0432.CCR-08-1694. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351771 Free article.
Expression and characterization of recombinant soluble human CD3 molecules: presentation of antigenic epitopes defined on the native TCR-CD3 complex.
Law CL, Hayden-Ledbetter M, Buckwalter S, McNeill L, Nguyen H, Habecker P, Thorne BA, Dua R, Ledbetter JA. Law CL, et al. Among authors: ledbetter ja. Int Immunol. 2002 Apr;14(4):389-400. doi: 10.1093/intimm/14.4.389. Int Immunol. 2002. PMID: 11934875
Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB.
Ye Z, Hellström I, Hayden-Ledbetter M, Dahlin A, Ledbetter JA, Hellström KE. Ye Z, et al. Among authors: ledbetter ja. Nat Med. 2002 Apr;8(4):343-8. doi: 10.1038/nm0402-343. Nat Med. 2002. PMID: 11927939
Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway.
Chaplin JW, Kasahara S, Clark EA, Ledbetter JA. Chaplin JW, et al. Among authors: ledbetter ja. J Immunol. 2011 Oct 15;187(8):4199-209. doi: 10.4049/jimmunol.1100198. Epub 2011 Sep 14. J Immunol. 2011. PMID: 21918197 Free PMC article.
B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells.
Nonoyama S, Hollenbaugh D, Aruffo A, Ledbetter JA, Ochs HD. Nonoyama S, et al. Among authors: ledbetter ja. J Exp Med. 1993 Sep 1;178(3):1097-102. doi: 10.1084/jem.178.3.1097. J Exp Med. 1993. PMID: 7688786 Free PMC article.
Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.
Tan P, Anasetti C, Hansen JA, Melrose J, Brunvand M, Bradshaw J, Ledbetter JA, Linsley PS. Tan P, et al. Among authors: ledbetter ja. J Exp Med. 1993 Jan 1;177(1):165-73. doi: 10.1084/jem.177.1.165. J Exp Med. 1993. PMID: 7678111 Free PMC article.
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