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356 results
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beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland.
Michaelson JS, Leder P. Michaelson JS, et al. Among authors: leder p. Oncogene. 2001 Aug 23;20(37):5093-9. doi: 10.1038/sj.onc.1204586. Oncogene. 2001. PMID: 11526497
Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis.
Brodie SG, Xu X, Li C, Kuo A, Leder P, Deng CX. Brodie SG, et al. Among authors: leder p. Oncogene. 2001 Mar 22;20(12):1445-54. doi: 10.1038/sj.onc.1204222. Oncogene. 2001. PMID: 11313888
P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.
Ridgeway AG, McMenamin J, Leder P. Ridgeway AG, et al. Among authors: leder p. Oncogene. 2006 Jun 15;25(25):3518-27. doi: 10.1038/sj.onc.1209391. Epub 2006 Jan 23. Oncogene. 2006. PMID: 16434961
Mitochondriotoxic compounds for cancer therapy.
Fantin VR, Leder P. Fantin VR, et al. Among authors: leder p. Oncogene. 2006 Aug 7;25(34):4787-97. doi: 10.1038/sj.onc.1209599. Oncogene. 2006. PMID: 16892091 Review.
Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency.
Leder A, McMenamin J, Zhou F, Moran JL, Beier DR, Leder P. Leder A, et al. Among authors: leder p. Oncogene. 2008 Apr 10;27(17):2456-65. doi: 10.1038/sj.onc.1210866. Epub 2007 Oct 22. Oncogene. 2008. PMID: 17952114 Free article.
The int-2 gene product acts as an epithelial growth factor in transgenic mice.
Muller WJ, Lee FS, Dickson C, Peters G, Pattengale P, Leder P. Muller WJ, et al. Among authors: leder p. EMBO J. 1990 Mar;9(3):907-13. EMBO J. 1990. PMID: 1690126 Free PMC article.
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene.
Muller WJ, Sinn E, Pattengale PK, Wallace R, Leder P. Muller WJ, et al. Among authors: leder p. Cell. 1988 Jul 1;54(1):105-15. doi: 10.1016/0092-8674(88)90184-5. Cell. 1988. PMID: 2898299
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant.
Flanagan JG, Chan DC, Leder P. Flanagan JG, et al. Among authors: leder p. Cell. 1991 Mar 8;64(5):1025-35. doi: 10.1016/0092-8674(91)90326-t. Cell. 1991. PMID: 1705866
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway.
Reizis B, Leder P. Reizis B, et al. Among authors: leder p. Genes Dev. 2002 Feb 1;16(3):295-300. doi: 10.1101/gad.960702. Genes Dev. 2002. PMID: 11825871 Free PMC article.
Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis.
Leder A, Lebel M, Zhou F, Fontaine K, Bishop A, Leder P. Leder A, et al. Among authors: leder p. Oncogene. 2002 Sep 26;21(43):6657-68. doi: 10.1038/sj.onc.1205795. Oncogene. 2002. PMID: 12242664
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