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Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice.
Lane TF, Leder P. Lane TF, et al. Among authors: leder p. Oncogene. 1997 Oct;15(18):2133-44. doi: 10.1038/sj.onc.1201593. Oncogene. 1997. PMID: 9393971
Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon.
Elson A, Leder P. Elson A, et al. Among authors: leder p. Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12235-9. doi: 10.1073/pnas.92.26.12235. Proc Natl Acad Sci U S A. 1995. PMID: 8618876 Free PMC article.
Allelic exclusion in transgenic mice carrying mutant human IgM genes.
Nussenzweig MC, Shaw AC, Sinn E, Campos-Torres J, Leder P. Nussenzweig MC, et al. Among authors: leder p. J Exp Med. 1988 Jun 1;167(6):1969-74. doi: 10.1084/jem.167.6.1969. J Exp Med. 1988. PMID: 3133444 Free PMC article.
beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland.
Michaelson JS, Leder P. Michaelson JS, et al. Among authors: leder p. Oncogene. 2001 Aug 23;20(37):5093-9. doi: 10.1038/sj.onc.1204586. Oncogene. 2001. PMID: 11526497
Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis.
Brodie SG, Xu X, Li C, Kuo A, Leder P, Deng CX. Brodie SG, et al. Among authors: leder p. Oncogene. 2001 Mar 22;20(12):1445-54. doi: 10.1038/sj.onc.1204222. Oncogene. 2001. PMID: 11313888
P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.
Ridgeway AG, McMenamin J, Leder P. Ridgeway AG, et al. Among authors: leder p. Oncogene. 2006 Jun 15;25(25):3518-27. doi: 10.1038/sj.onc.1209391. Epub 2006 Jan 23. Oncogene. 2006. PMID: 16434961
Mitochondriotoxic compounds for cancer therapy.
Fantin VR, Leder P. Fantin VR, et al. Among authors: leder p. Oncogene. 2006 Aug 7;25(34):4787-97. doi: 10.1038/sj.onc.1209599. Oncogene. 2006. PMID: 16892091 Review.
Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency.
Leder A, McMenamin J, Zhou F, Moran JL, Beier DR, Leder P. Leder A, et al. Among authors: leder p. Oncogene. 2008 Apr 10;27(17):2456-65. doi: 10.1038/sj.onc.1210866. Epub 2007 Oct 22. Oncogene. 2008. PMID: 17952114 Free article.
Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice.
Kwan H, Pecenka V, Tsukamoto A, Parslow TG, Guzman R, Lin TP, Muller WJ, Lee FS, Leder P, Varmus HE. Kwan H, et al. Among authors: leder p. Mol Cell Biol. 1992 Jan;12(1):147-54. doi: 10.1128/mcb.12.1.147. Mol Cell Biol. 1992. PMID: 1530875 Free PMC article.
The int-2 gene product acts as an epithelial growth factor in transgenic mice.
Muller WJ, Lee FS, Dickson C, Peters G, Pattengale P, Leder P. Muller WJ, et al. Among authors: leder p. EMBO J. 1990 Mar;9(3):907-13. EMBO J. 1990. PMID: 1690126 Free PMC article.
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