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Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells.
Park BC, Bosire KO, Lee ES, Lee YS, Kim JA. Park BC, et al. Among authors: lee es, lee ys. Cancer Lett. 2005 Jan 31;218(1):81-90. doi: 10.1016/j.canlet.2004.06.039. Cancer Lett. 2005. PMID: 15639343
Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells.
Lee YS, Jin DQ, Kwon EJ, Park SH, Lee ES, Jeong TC, Nam DH, Huh K, Kim JA. Lee YS, et al. Among authors: lee es. Cancer Lett. 2002 Dec 1;186(1):83-91. doi: 10.1016/s0304-3835(02)00260-4. Cancer Lett. 2002. PMID: 12183079
Inhibition of ultraviolet-A-modulated signaling pathways by asiatic acid and ursolic acid in HaCaT human keratinocytes.
Soo Lee Y, Jin DQ, Beak SM, Lee ES, Kim JA. Soo Lee Y, et al. Among authors: lee es. Eur J Pharmacol. 2003 Aug 29;476(3):173-8. doi: 10.1016/s0014-2999(03)02177-0. Eur J Pharmacol. 2003. PMID: 12969763
Inhibition of nitric oxide and tumor necrosis factor-alpha (TNF-alpha) production by propenone compound through blockade of nuclear factor (NF)-kappa B activation in cultured murine macrophages.
Lee ES, Ju HK, Moon TC, Lee E, Jahng Y, Lee SH, Son JK, Baek SH, Chang HW. Lee ES, et al. Among authors: lee e, lee sh. Biol Pharm Bull. 2004 May;27(5):617-20. doi: 10.1248/bpb.27.617. Biol Pharm Bull. 2004. PMID: 15133232
Structure-related cytotoxicity and anti-hepatofibric effect of asiatic acid derivatives in rat hepatic stellate cell-line, HSC-T6.
Dong MS, Jung SH, Kim HJ, Kim JR, Zhao LX, Lee ES, Lee EJ, Yi JB, Lee N, Cho YB, Kwak WJ, Park YI. Dong MS, et al. Among authors: lee es, lee ej, lee n. Arch Pharm Res. 2004 May;27(5):512-7. doi: 10.1007/BF02980124. Arch Pharm Res. 2004. PMID: 15202556
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
Park BC, Paek SH, Lee YS, Kim SJ, Lee ES, Choi HG, Yong CS, Kim JA. Park BC, et al. Among authors: lee ys, lee es. Biol Pharm Bull. 2007 Jan;30(1):176-9. doi: 10.1248/bpb.30.176. Biol Pharm Bull. 2007. PMID: 17202682
Modification of C2 functional group on asiatic acid and the evaluation of hepatoprotective effects.
Jeong BS, Lee MK, Kim YC, Lee ES. Jeong BS, et al. Among authors: lee mk, lee es. Arch Pharm Res. 2007 Mar;30(3):282-9. doi: 10.1007/BF02977607. Arch Pharm Res. 2007. PMID: 17424932
1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
Park BC, Thapa D, Lee YS, Kwak MK, Lee ES, Choi HG, Yong CS, Kim JA. Park BC, et al. Among authors: lee ys, lee es. Eur J Pharmacol. 2007 Jul 19;567(3):193-7. doi: 10.1016/j.ejphar.2007.04.014. Epub 2007 Apr 21. Eur J Pharmacol. 2007. PMID: 17507007
Activation of the Nrf2-antioxidant system by a novel cyclooxygenase-2 inhibitor furan-2-yl-3-pyridin-2-yl-propenone: implication in anti-inflammatory function by Nrf2 activator.
Manandhar S, You A, Lee ES, Kim JA, Kwak MK. Manandhar S, et al. Among authors: lee es. J Pharm Pharmacol. 2008 Jul;60(7):879-87. doi: 10.1211/jpp.60.7.0009. J Pharm Pharmacol. 2008. PMID: 18549674
The anti-angiogenic effects of 1-furan-2-yl-3-pyridin-2-yl-propenone are mediated through the suppression of both VEGF production and VEGF-induced signaling.
Park BC, Park SY, Lee JS, Mousa SA, Kim JT, Kwak MK, Kang KW, Lee ES, Choi HG, Yong CS, Kim JA. Park BC, et al. Among authors: lee js, lee es. Vascul Pharmacol. 2009 Mar-Apr;50(3-4):123-31. doi: 10.1016/j.vph.2008.11.006. Epub 2008 Nov 28. Vascul Pharmacol. 2009. PMID: 19068239
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