Lee HY - Search Results

1

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Lee HY, et al. Cell Metab. 2010 Dec 1;12(6):668-74. doi: 10.1016/j.cmet.2010.11.004. Cell Metab. 2010. PMID: 21109199 Free PMC article.

2

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.

Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI. Choi CS, et al. Among authors: lee hy. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19926-31. doi: 10.1073/pnas.0810339105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066218 Free PMC article.

3

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency.

Jaworski K, Ahmadian M, Duncan RE, Sarkadi-Nagy E, Varady KA, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Kim KH, de Val S, Kang C, Sul HS. Jaworski K, et al. Among authors: lee hy. Nat Med. 2009 Feb;15(2):159-68. doi: 10.1038/nm.1904. Epub 2009 Jan 11. Nat Med. 2009. PMID: 19136964 Free PMC article.

4

Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.

Chutkow WA, Birkenfeld AL, Brown JD, Lee HY, Frederick DW, Yoshioka J, Patwari P, Kursawe R, Cushman SW, Plutzky J, Shulman GI, Samuel VT, Lee RT. Chutkow WA, et al. Among authors: lee hy, lee rt. Diabetes. 2010 Jun;59(6):1424-34. doi: 10.2337/db09-1212. Epub 2010 Mar 18. Diabetes. 2010. PMID: 20299477 Free PMC article.

5

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain.

Jornayvaz FR, Jurczak MJ, Lee HY, Birkenfeld AL, Frederick DW, Zhang D, Zhang XM, Samuel VT, Shulman GI. Jornayvaz FR, et al. Among authors: lee hy. Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E808-15. doi: 10.1152/ajpendo.00361.2010. Epub 2010 Aug 31. Am J Physiol Endocrinol Metab. 2010. PMID: 20807839 Free PMC article.

6

Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues.

Lin HV, Ren H, Samuel VT, Lee HY, Lu TY, Shulman GI, Accili D. Lin HV, et al. Among authors: lee hy. Diabetes. 2011 Mar;60(3):700-9. doi: 10.2337/db10-1056. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266328 Free PMC article.

7

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function.

Jurczak MJ, Lee HY, Birkenfeld AL, Jornayvaz FR, Frederick DW, Pongratz RL, Zhao X, Moeckel GW, Samuel VT, Whaley JM, Shulman GI, Kibbey RG. Jurczak MJ, et al. Among authors: lee hy. Diabetes. 2011 Mar;60(3):890-8. doi: 10.2337/db10-1328. Diabetes. 2011. PMID: 21357472 Free PMC article.

8

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2.

Jornayvaz FR, Birkenfeld AL, Jurczak MJ, Kanda S, Guigni BA, Jiang DC, Zhang D, Lee HY, Samuel VT, Shulman GI. Jornayvaz FR, et al. Among authors: lee hy. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5748-52. doi: 10.1073/pnas.1103451108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21436037 Free PMC article.

9

Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype.

Ahmadian M, Abbott MJ, Tang T, Hudak CS, Kim Y, Bruss M, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Wang Y, Duncan RE, Kang C, Sul HS. Ahmadian M, et al. Among authors: lee hy. Cell Metab. 2011 Jun 8;13(6):739-48. doi: 10.1016/j.cmet.2011.05.002. Cell Metab. 2011. PMID: 21641555 Free PMC article.

10

Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance.

Lee HY, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Kanda S, Popov V, Frederick DW, Zhang D, Guigni B, Bharadwaj KG, Choi CS, Goldberg IJ, Park JH, Petersen KF, Samuel VT, Shulman GI. Lee HY, et al. Hepatology. 2011 Nov;54(5):1650-60. doi: 10.1002/hep.24571. Epub 2011 Aug 19. Hepatology. 2011. PMID: 21793029 Free PMC article.

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