Insulin receptor autophosphorylation occurs asymmetrically.
Lee J, O'Hare T, Pilch PF, Shoelson SE.
Lee J, et al.
J Biol Chem. 1993 Feb 25;268(6):4092-8.
J Biol Chem. 1993.
PMID: 8440700
Free article.
The unoccupied insulin receptor is a structurally symmetric, disulfide-linked dimer, comprising two alpha beta halves, each with a potential insulin binding alpha subunit and a kinase active beta subunit. In the accompanying paper (Shoelson, S. E., Lee, J., Lynch, C …
The unoccupied insulin receptor is a structurally symmetric, disulfide-linked dimer, comprising two alpha beta halves, each with a potential …