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Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage.
Kim H, Lee GR, Kim J, Baek JY, Jo YJ, Hong SE, Kim SH, Lee J, Lee HI, Park SK, Kim HM, Lee HJ, Chang TS, Rhee SG, Lee JS, Jeong W. Kim H, et al. Among authors: lee js, lee gr, lee j, lee hi, lee hj. Free Radic Biol Med. 2016 Feb;91:264-74. doi: 10.1016/j.freeradbiomed.2015.12.023. Epub 2015 Dec 23. Free Radic Biol Med. 2016. PMID: 26721593
Caspase-9 activation and Apaf-1 cleavage by MMP-3.
Kim EM, Shin EJ, Lee JA, Son HJ, Choi DH, Han JM, Hwang O. Kim EM, et al. Biochem Biophys Res Commun. 2014 Oct 24;453(3):563-8. doi: 10.1016/j.bbrc.2014.09.124. Epub 2014 Oct 5. Biochem Biophys Res Commun. 2014. PMID: 25285627
Dehydrocostus lactone suppresses osteoclast differentiation by regulating NFATc1 and inhibits osteoclast activation through modulating migration and lysosome function.
Lee HI, Lee J, Hwang D, Lee GR, Kim N, Kwon M, Lee H, Piao D, Kim HJ, Kim NY, Kim HS, Seo EK, Kang D, Jeong W. Lee HI, et al. Among authors: lee h, lee gr, lee j. FASEB J. 2019 Aug;33(8):9685-9694. doi: 10.1096/fj.201900862R. Epub 2019 May 30. FASEB J. 2019. PMID: 31145860
These results indicate that DL has therapeutic potential to treat bone diseases caused by excessive or hyperactive osteoclasts.-Lee, H. I., Lee, J., Hwang, D., Lee, G.-R., Kim, N., Kwon, M., Lee, H., Piao, D., Kim, H. J., Kim, N. Y., Kim, …
These results indicate that DL has therapeutic potential to treat bone diseases caused by excessive or hyperactive osteoclasts.-Lee, …
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