Lee JH - Search Results

1

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. Lee JH, et al. Cell Metab. 2012 Sep 5;16(3):311-21. doi: 10.1016/j.cmet.2012.08.004. Cell Metab. 2012. PMID: 22958918 Free PMC article.

2

The Ras-JNK pathway is involved in shear-induced gene expression.

Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, Chien S. Li YS, et al. Mol Cell Biol. 1996 Nov;16(11):5947-54. doi: 10.1128/MCB.16.11.5947. Mol Cell Biol. 1996. PMID: 8887624 Free PMC article.

3

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M. Park EJ, et al. Among authors: lee jh. Cell. 2010 Jan 22;140(2):197-208. doi: 10.1016/j.cell.2009.12.052. Cell. 2010. PMID: 20141834 Free PMC article.

4

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.

Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Lee JH, et al. Science. 2010 Mar 5;327(5970):1223-8. doi: 10.1126/science.1182228. Science. 2010. PMID: 20203043 Free PMC article.

5

Sestrins at the crossroad between stress and aging.

Lee JH, Bodmer R, Bier E, Karin M. Lee JH, et al. Aging (Albany NY). 2010 Jun;2(6):369-74. doi: 10.18632/aging.100157. Aging (Albany NY). 2010. PMID: 20606249 Free PMC article. Review.

6

Stressin' Sestrins take an aging fight.

Budanov AV, Lee JH, Karin M. Budanov AV, et al. Among authors: lee jh. EMBO Mol Med. 2010 Oct;2(10):388-400. doi: 10.1002/emmm.201000097. EMBO Mol Med. 2010. PMID: 20878915 Free PMC article. Review.

7

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.

Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, Moscat J, Diaz-Meco M, Dawson D, Erkan M, Kleeff J, Karin M. Li N, et al. Among authors: lee jh. J Clin Invest. 2013 May;123(5):2231-43. doi: 10.1172/JCI64498. Epub 2013 Apr 8. J Clin Invest. 2013. PMID: 23563314 Free PMC article.

8

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging.

Kim M, Park HL, Park HW, Ro SH, Nam SG, Reed JM, Guan JL, Lee JH. Kim M, et al. Among authors: lee jh. Autophagy. 2013 Aug;9(8):1201-13. doi: 10.4161/auto.24811. Epub 2013 May 14. Autophagy. 2013. PMID: 23819996 Free PMC article.

9

Sestrins orchestrate cellular metabolism to attenuate aging.

Lee JH, Budanov AV, Karin M. Lee JH, et al. Cell Metab. 2013 Dec 3;18(6):792-801. doi: 10.1016/j.cmet.2013.08.018. Epub 2013 Sep 19. Cell Metab. 2013. PMID: 24055102 Free PMC article. Review.

10

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species.

Ro SH, Nam M, Jang I, Park HW, Park H, Semple IA, Kim M, Kim JS, Park H, Einat P, Damari G, Golikov M, Feinstein E, Lee JH. Ro SH, et al. Among authors: lee jh. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7849-54. doi: 10.1073/pnas.1401787111. Epub 2014 May 13. Proc Natl Acad Sci U S A. 2014. PMID: 24825887 Free PMC article.

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