Lee KG - Search Results

1

BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses.

Althubiti M, Rada M, Samuel J, Escorsa JM, Najeeb H, Lee KG, Lam KP, Jones GD, Barlev NA, Macip S. Althubiti M, et al. Among authors: lee kg. Cancer Res. 2016 Sep 15;76(18):5405-14. doi: 10.1158/0008-5472.CAN-16-0690. Epub 2016 Jul 26. Cancer Res. 2016. PMID: 27630139

2

BTK blocks the inhibitory effects of MDM2 on p53 activity.

Rada M, Althubiti M, Ekpenyong-Akiba AE, Lee KG, Lam KP, Fedorova O, Barlev NA, Macip S. Rada M, et al. Among authors: lee kg. Oncotarget. 2017 Nov 20;8(63):106639-106647. doi: 10.18632/oncotarget.22543. eCollection 2017 Dec 5. Oncotarget. 2017. PMID: 29290977 Free PMC article.

3

Bruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells.

Lee KG, Xu S, Wong ET, Tergaonkar V, Lam KP. Lee KG, et al. J Biol Chem. 2008 Apr 25;283(17):11189-98. doi: 10.1074/jbc.M708516200. Epub 2008 Feb 13. J Biol Chem. 2008. PMID: 18276597 Free article.

4

BTK: sensing pathogenic nucleic acids.

Lee KG, Lam KP. Lee KG, et al. Oncotarget. 2015 Aug 21;6(24):19948-9. doi: 10.18632/oncotarget.4778. Oncotarget. 2015. PMID: 26196947 Free PMC article. No abstract available.

5

Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells.

Li YF, Lee KG, Ou X, Lam KP. Li YF, et al. Among authors: lee kg. PLoS One. 2014 Aug 29;9(8):e105420. doi: 10.1371/journal.pone.0105420. eCollection 2014. PLoS One. 2014. PMID: 25170774 Free PMC article.

6

Combined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stage.

Xu S, Lee KG, Huo J, Kurosaki T, Lam KP. Xu S, et al. Among authors: lee kg. Blood. 2007 Apr 15;109(8):3377-84. doi: 10.1182/blood-2006-07-036418. Epub 2006 Dec 12. Blood. 2007. PMID: 17164342 Free article.

7

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.

Xu S, Huo J, Lee KG, Kurosaki T, Lam KP. Xu S, et al. Among authors: lee kg. J Biol Chem. 2009 Mar 13;284(11):7038-46. doi: 10.1074/jbc.M806650200. Epub 2009 Jan 9. J Biol Chem. 2009. PMID: 19136564 Free PMC article.

8

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response.

Lee KG, Xu S, Kang ZH, Huo J, Huang M, Liu D, Takeuchi O, Akira S, Lam KP. Lee KG, et al. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5791-6. doi: 10.1073/pnas.1119238109. Epub 2012 Mar 27. Proc Natl Acad Sci U S A. 2012. PMID: 22454496 Free PMC article.

9

DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.

Kim SS, Lee KG, Chin CS, Ng SK, Pereira NA, Xu S, Lam KP. Kim SS, et al. Among authors: lee kg. J Immunol. 2014 Jul 15;193(2):840-8. doi: 10.4049/jimmunol.1301601. Epub 2014 Jun 13. J Immunol. 2014. PMID: 24929003

10

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

Lee KG, Kim SS, Kui L, Voon DC, Mauduit M, Bist P, Bi X, Pereira NA, Liu C, Sukumaran B, Rénia L, Ito Y, Lam KP. Lee KG, et al. Cell Rep. 2015 Feb 24;10(7):1055-65. doi: 10.1016/j.celrep.2015.01.039. Epub 2015 Feb 19. Cell Rep. 2015. PMID: 25704810 Free article.

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