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Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Parra Bravo C, Giani AM, Perez JM, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Parra Bravo C, et al. Among authors: lee vmy. Cell. 2024 Mar 28:S0092-8674(24)00306-4. doi: 10.1016/j.cell.2024.03.015. Online ahead of print. Cell. 2024. PMID: 38582079 Free article.
MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons.
Xu H, Qiu Q, Hu P, Hoxha K, Jang E, O'Reilly M, Kim C, He Z, Marotta N, Changolkar L, Zhang B, Wu H, Schellenberg GD, Kraemer B, Luk KC, Lee EB, Trojanowski JQ, Brunden KR, Lee VM. Xu H, et al. Among authors: lee vm. Acta Neuropathol. 2024 Mar 12;147(1):55. doi: 10.1007/s00401-024-02703-3. Acta Neuropathol. 2024. PMID: 38472475 Free PMC article.
ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's Disease.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Bhatia TN, Xu S, Belchikov N, He Y, Pang AP, Lanjewar SN, Jarroux J, Joglekar A, Milner TA, Ndhlovu LC, Zhang J, Butelman E, Sloan SA, Lee VM, Gan L, Tilgner HU. Hu W, et al. Among authors: lee vm. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581897. doi: 10.1101/2024.02.24.581897. bioRxiv. 2024. PMID: 38464236 Free PMC article. Preprint.
Author Correction: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology.
Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR. Balana AT, et al. Among authors: lee vm. Nat Chem Biol. 2024 Feb 27. doi: 10.1038/s41589-024-01587-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38413747 No abstract available.
1,077 results