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Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors.
Bioorg Med Chem. 2015 Jan 1;23(1):231-40. doi: 10.1016/j.bmc.2014.11.004. Epub 2014 Nov 13.
Bioorg Med Chem. 2015.
PMID: 25468034
IND-2, a pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells.
Karthikeyan C, Lee C, Moore J, Mittal R, Suswam EA, Abbott KL, Pondugula SR, Manne U, Narayanan NK, Trivedi P, Tiwari AK.
Karthikeyan C, et al.
Bioorg Med Chem. 2015 Feb 1;23(3):602-11. doi: 10.1016/j.bmc.2014.11.043. Epub 2014 Dec 8.
Bioorg Med Chem. 2015.
PMID: 25537531
Free PMC article.
The compounds were evaluated for activity against colon (HCT-116 and S1-MI-80), prostate (PC3 and DU-145), breast (MCF-7 and MDAMB-231), ovarian (ov2008 and A2780), and hepatocellular (HepG2) cancer cells and against non-cancerous Madin Darby canine kidney (MDCK), mouse em …
The compounds were evaluated for activity against colon (HCT-116 and S1-MI-80), prostate (PC3 and DU-145), breast (MCF-7 and MDAMB-231 …
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