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The two-state model of receptor activation.
Leff P. Leff P. Trends Pharmacol Sci. 1995 Mar;16(3):89-97. doi: 10.1016/s0165-6147(00)88989-0. Trends Pharmacol Sci. 1995. PMID: 7540781
Nomenclature and classification of purinoceptors.
Fredholm BB, Abbracchio MP, Burnstock G, Daly JW, Harden TK, Jacobson KA, Leff P, Williams M. Fredholm BB, et al. Among authors: leff p. Pharmacol Rev. 1994 Jun;46(2):143-56. Pharmacol Rev. 1994. PMID: 7938164 Free PMC article. Review. No abstract available.
Promiscuity, pre-coupling and instability.
Leff P, Scaramellini C. Leff P, et al. Trends Pharmacol Sci. 1998 Jan;19(1):13. doi: 10.1016/s0165-6147(97)01150-4. Trends Pharmacol Sci. 1998. PMID: 9509895 No abstract available.
A three-state receptor model of agonist action.
Leff P, Scaramellini C, Law C, McKechnie K. Leff P, et al. Trends Pharmacol Sci. 1997 Oct;18(10):355-62. doi: 10.1016/s0165-6147(97)01105-x. Trends Pharmacol Sci. 1997. PMID: 9357320 Review.
Further concerns over Cheng-Prusoff analysis.
Leff P, Dougall IG. Leff P, et al. Trends Pharmacol Sci. 1993 Apr;14(4):110-2. doi: 10.1016/0165-6147(93)90080-4. Trends Pharmacol Sci. 1993. PMID: 8516953
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