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AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes.
Canuel M, Lefrancois S, Zeng J, Morales CR. Canuel M, et al. Among authors: lefrancois s. Biochem Biophys Res Commun. 2008 Feb 15;366(3):724-30. doi: 10.1016/j.bbrc.2007.12.015. Epub 2007 Dec 17. Biochem Biophys Res Commun. 2008. PMID: 18078806
Role of sphingolipids in the transport of prosaposin to the lysosomes.
Lefrancois S, Michaud L, Potier M, Igdoura S, Morales CR. Lefrancois S, et al. J Lipid Res. 1999 Sep;40(9):1593-603. J Lipid Res. 1999. PMID: 10484606
Biogenesis of lysosomes by endocytic flow of plasma membrane.
Morales CR, Zhao Q, Lefrancois S. Morales CR, et al. Among authors: lefrancois s. Biocell. 1999 Dec;23(3):149-60. Biocell. 1999. PMID: 10904540 Review.
Biogenesis of lysosomes in marshall cells and in cells of the male reproductive system.
Morales CR, Fuska J, Zhao Q, Lefrancois S. Morales CR, et al. Among authors: lefrancois s. Mol Reprod Dev. 2001 May;59(1):54-66. doi: 10.1002/mrd.1007. Mol Reprod Dev. 2001. PMID: 11335947
The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin.
Lefrancois S, May T, Knight C, Bourbeau D, Morales CR. Lefrancois S, et al. J Biol Chem. 2002 May 10;277(19):17188-99. doi: 10.1074/jbc.M200343200. Epub 2002 Feb 20. J Biol Chem. 2002. PMID: 11856752
The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin.
Lefrancois S, Zeng J, Hassan AJ, Canuel M, Morales CR. Lefrancois S, et al. EMBO J. 2003 Dec 15;22(24):6430-7. doi: 10.1093/emboj/cdg629. EMBO J. 2003. PMID: 14657016 Free PMC article.
An ear-core interaction regulates the recruitment of the AP-3 complex to membranes.
Lefrançois S, Janvier K, Boehm M, Ooi CE, Bonifacino JS. Lefrançois S, et al. Dev Cell. 2004 Oct;7(4):619-25. doi: 10.1016/j.devcel.2004.08.009. Dev Cell. 2004. PMID: 15469849
Inactivation of sortilin (a novel lysosomal sorting receptor) by dominant negative competition and RNA interference.
Lefrancois S, Canuel M, Zeng J, Morales CR. Lefrancois S, et al. Biol Proced Online. 2005;7:17-25. doi: 10.1251/bpo101. Epub 2005 Jan 25. Biol Proced Online. 2005. PMID: 15682222 Free PMC article.
The Arf GEF GBF1 is required for GGA recruitment to Golgi membranes.
Lefrançois S, McCormick PJ. Lefrançois S, et al. Traffic. 2007 Oct;8(10):1440-51. doi: 10.1111/j.1600-0854.2007.00623.x. Epub 2007 Jul 31. Traffic. 2007. PMID: 17666033
Palmitoylation controls recycling in lysosomal sorting and trafficking.
McCormick PJ, Dumaresq-Doiron K, Pluviose AS, Pichette V, Tosato G, Lefrancois S. McCormick PJ, et al. Among authors: lefrancois s. Traffic. 2008 Nov;9(11):1984-97. doi: 10.1111/j.1600-0854.2008.00814.x. Epub 2008 Aug 9. Traffic. 2008. PMID: 18817523 Free PMC article.
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