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1,628 results

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Page 1
Left Atrial Appendage Closure after Ablation for Atrial Fibrillation.
Wazni OM, Saliba WI, Nair DG, Marijon E, Schmidt B, Hounshell T, Ebelt H, Skurk C, Oza S, Patel C, Kanagasundram A, Sadhu A, Sundaram S, Osorio J, Mark G, Gupta M, DeLurgio DB, Olson J, Nielsen-Kudsk JE, Boersma LVA, Healey JS, Phillips KP, Asch FM, Wolski K, Roy K, Christen T, Sutton BS, Stein KM, Reddy VY; OPTION Trial Investigators. Wazni OM, et al. N Engl J Med. 2025 Apr 3;392(13):1277-1287. doi: 10.1056/NEJMoa2408308. Epub 2024 Nov 16. N Engl J Med. 2025. PMID: 39555822 Clinical Trial.
BACKGROUND: Oral anticoagulation is recommended after ablation for atrial fibrillation among patients at high risk for stroke. Left atrial appendage closure is a mechanical alternative to anticoagulation, but data regarding its use after atri …
BACKGROUND: Oral anticoagulation is recommended after ablation for atrial fibrillation among patients at high risk for stroke. Lef …
Device related thrombus after left atrial appendage closure: State of the art.
Yu J, Bai Y, Jiang LS. Yu J, et al. Pacing Clin Electrophysiol. 2021 Jul;44(7):1253-1258. doi: 10.1111/pace.14122. Epub 2020 Dec 10. Pacing Clin Electrophysiol. 2021. PMID: 33165978 Review.
Atrial fibrillation (AF), the most common arrhythmia, is a major cause of stroke and systemic embolism. Patients with AF are at higher risk of stroke with the left atrial appendage (LAA) being the most common site for thrombus formation. Although oral …
Atrial fibrillation (AF), the most common arrhythmia, is a major cause of stroke and systemic embolism. Patients with AF are at highe …
Left atrial appendage closure: patient, device and post-procedure drug selection.
Tzikas A, Bergmann MW. Tzikas A, et al. EuroIntervention. 2016 May 17;12 Suppl X:X48-X54. doi: 10.4244/EIJV12SXA10. EuroIntervention. 2016. PMID: 27174112 Free article. Review.
Left atrial appendage closure (LAAC), a device-based therapy for stroke prevention in patients with atrial fibrillation, is considered an alternative to oral anticoagulation therapy, particularly for patients at high risk of bleeding. ... …
Left atrial appendage closure (LAAC), a device-based therapy for stroke prevention in patients with at …
Antithrombotic Therapy and Device-Related Thrombosis Following Endovascular Left Atrial Appendage Closure.
Saw J, Nielsen-Kudsk JE, Bergmann M, Daniels MJ, Tzikas A, Reisman M, Rana BS. Saw J, et al. JACC Cardiovasc Interv. 2019 Jun 10;12(11):1067-1076. doi: 10.1016/j.jcin.2018.11.001. Epub 2019 May 15. JACC Cardiovasc Interv. 2019. PMID: 31103535 Free article. Review.
OBJECTIVES: The aim of this study is to review the evidence on the use of antithrombotic therapy and risk of device-related thrombosis after left atrial appendage closure. BACKGROUND: Left atrial appendage closure (LA …
OBJECTIVES: The aim of this study is to review the evidence on the use of antithrombotic therapy and risk of device-related thrombosi …
Left atrial appendage closure for stroke prevention in atrial fibrillation: current status and perspectives.
Landmesser U, Skurk C, Tzikas A, Falk V, Reddy VY, Windecker S. Landmesser U, et al. Eur Heart J. 2024 Aug 21;45(32):2914-2932. doi: 10.1093/eurheartj/ehae398. Eur Heart J. 2024. PMID: 39027946 Free PMC article. Review.
Atrial fibrillation (AF) is associated with an increased risk of stroke and systemic embolism, and the left atrial appendage (LAA) has been identified as a principal source of thromboembolism in these patients. While oral anticoagulation is the current …
Atrial fibrillation (AF) is associated with an increased risk of stroke and systemic embolism, and the left atrial a …
The WATCHMAN left atrial appendage closure device for patients with atrial fibrillation: current status and future perspectives.
Wintgens LIS, Maarse M, Swaans MJ, Rensing BJWM, Van Dijk VF, Boersma LVA. Wintgens LIS, et al. Expert Rev Med Devices. 2020 Jul;17(7):615-626. doi: 10.1080/17434440.2020.1781615. Epub 2020 Jul 27. Expert Rev Med Devices. 2020. PMID: 32543911 Review.
The left atrial appendage (LAA) is the main source of thrombus formation in AF patients. The WATCHMAN percutaneous LAA closure (LAAC) device may serve as an alternative to OAC overcoming disadvantages including the risk of (major) bleeding. ...O …
The left atrial appendage (LAA) is the main source of thrombus formation in AF patients. The WATCHMAN percutaneous LAA …
One-Year Outcomes After Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: A Prespecified Analysis of the SWISS-APERO Randomized Clinical Trial.
Galea R, Meneveau N, De Marco F, Aminian A, Heg D, Chalkou K, Gräni C, Anselme F, Franzone A, Vranckx P, Fischer U, Bedogni F, Räber L, Valgimigli M. Galea R, et al. Circulation. 2024 Feb 6;149(6):484-486. doi: 10.1161/CIRCULATIONAHA.123.067599. Epub 2023 Oct 24. Circulation. 2024. PMID: 37875064 Free article. Clinical Trial. No abstract available.
Left Atrial Appendage Closure Device in Atrial Fibrillation.
Giudici MC, Bhave PD. Giudici MC, et al. Cardiol Clin. 2017 May;35(2):297-300. doi: 10.1016/j.ccl.2016.12.011. Cardiol Clin. 2017. PMID: 28411903 Review.
Recent studies have questioned the temporal relationship between the two, which also questions causation. Left atrial appendage closure is an attractive, but unproven technology when compared with the 50-year experience with warfarin. In a patient who …
Recent studies have questioned the temporal relationship between the two, which also questions causation. Left atrial appen …
The WATCHMAN Left Atrial Appendage Closure Device: Technical Considerations and Procedural Approach.
Price MJ. Price MJ. Interv Cardiol Clin. 2018 Apr;7(2):201-212. doi: 10.1016/j.iccl.2017.12.010. Interv Cardiol Clin. 2018. PMID: 29526288 Review.
Randomized clinical trials have demonstrated that left atrial appendage (LAA) closure with the WATCHMAN device provides stroke prevention in nonvalvular atrial fibrillation while significantly reducing morality and major bleeding. ...
Randomized clinical trials have demonstrated that left atrial appendage (LAA) closure with the WATCHMAN devic …
Safety and efficacy of left atrial appendage closure using an epicardial suture snaring device: Systematic review and current status.
Sabzwari SRA, Mehta NA, Garg L, Racharla L, Kurtz E, Afzal MR, Turagam MK, Lakkireddy D. Sabzwari SRA, et al. J Cardiovasc Electrophysiol. 2021 Aug;32(8):2189-2198. doi: 10.1111/jce.15132. Epub 2021 Jul 7. J Cardiovasc Electrophysiol. 2021. PMID: 34164881
The primary efficacy outcome evaluated was left atrial appendage closure with residual flow 1 mm. Safety outcomes evaluated were periprocedural and long term complications after device placement. ...Oral anticoagulation use decreased from 44.7% …
The primary efficacy outcome evaluated was left atrial appendage closure with residual flow 1 mm. Safety outcome …
1,628 results