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CTL activation is induced by cross-linking of TCR/MHC-peptide-CD8/p56lck adducts in rafts.
Doucey MA, Legler DF, Boucheron N, Cerottini JC, Bron C, Luescher IF. Doucey MA, et al. Eur J Immunol. 2001 May;31(5):1561-70. doi: 10.1002/1521-4141(200105)31:5<1561::AID-IMMU1561>3.0.CO;2-W. Eur J Immunol. 2001. PMID: 11465114
Association of the Epstein-Barr virus latent membrane protein 1 with lipid rafts is mediated through its N-terminal region.
Rothenberger S, Rousseaux M, Knecht H, Bender FC, Legler DF, Bron C. Rothenberger S, et al. Cell Mol Life Sci. 2002 Jan;59(1):171-80. doi: 10.1007/s00018-002-8413-y. Cell Mol Life Sci. 2002. PMID: 11846027
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation.
Gaide O, Favier B, Legler DF, Bonnet D, Brissoni B, Valitutti S, Bron C, Tschopp J, Thome M. Gaide O, et al. Nat Immunol. 2002 Sep;3(9):836-43. doi: 10.1038/ni830. Epub 2002 Aug 5. Nat Immunol. 2002. PMID: 12154360
The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.
Doucey MA, Legler DF, Faroudi M, Boucheron N, Baumgaertner P, Naeher D, Cebecauer M, Hudrisier D, Rüegg C, Palmer E, Valitutti S, Bron C, Luescher IF. Doucey MA, et al. J Biol Chem. 2003 Jul 18;278(29):26983-91. doi: 10.1074/jbc.M302709200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690105
PrPc capping in T cells promotes its association with the lipid raft proteins reggie-1 and reggie-2 and leads to signal transduction.
Stuermer CA, Langhorst MF, Wiechers MF, Legler DF, Von Hanwehr SH, Guse AH, Plattner H. Stuermer CA, et al. FASEB J. 2004 Nov;18(14):1731-3. doi: 10.1096/fj.04-2150fje. Epub 2004 Sep 2. FASEB J. 2004. PMID: 15345693
Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.
Legler DF, Doucey MA, Schneider P, Chapatte L, Bender FC, Bron C. Legler DF, et al. FASEB J. 2005 Jan;19(1):73-5. doi: 10.1096/fj.03-1338fje. Epub 2004 Oct 29. FASEB J. 2005. PMID: 15516372
Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts.
Nachbur U, Kassahn D, Yousefi S, Legler DF, Brunner T. Nachbur U, et al. Blood. 2006 Apr 1;107(7):2790-6. doi: 10.1182/blood-2005-07-2744. Epub 2005 Dec 6. Blood. 2006. PMID: 16332972
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