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Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.
Maschmeyer P, Petkau G, Siracusa F, Zimmermann J, Zügel F, Kühl AA, Lehmann K, Schimmelpfennig S, Weber M, Haftmann C, Riedel R, Bardua M, Heinz GA, Tran CL, Hoyer BF, Hiepe F, Herzog S, Wittmann J, Rajewsky N, Melchers FG, Chang HD, Radbruch A, Mashreghi MF. Maschmeyer P, et al. Among authors: lehmann k. J Autoimmun. 2018 May;89:41-52. doi: 10.1016/j.jaut.2017.11.005. Epub 2017 Dec 1. J Autoimmun. 2018. PMID: 29183643 Free PMC article.
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF. Haftmann C, et al. Among authors: lehmann k. Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22. Eur J Immunol. 2015. PMID: 25486906 Free PMC article.
MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes.
Bardua M, Haftmann C, Durek P, Westendorf K, Buttgereit A, Tran CL, McGrath M, Weber M, Lehmann K, Addo RK, Heinz GA, Stittrich AB, Maschmeyer P, Radbruch H, Lohoff M, Chang HD, Radbruch A, Mashreghi MF. Bardua M, et al. Among authors: lehmann k. Front Immunol. 2018 Dec 6;9:2813. doi: 10.3389/fimmu.2018.02813. eCollection 2018. Front Immunol. 2018. PMID: 30574141 Free PMC article.
T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.
Zimmermann J, Kühl AA, Weber M, Grün JR, Löffler J, Haftmann C, Riedel R, Maschmeyer P, Lehmann K, Westendorf K, Mashreghi MF, Löhning M, Mack M, Radbruch A, Chang HD. Zimmermann J, et al. Among authors: lehmann k. Mucosal Immunol. 2016 Nov;9(6):1487-1499. doi: 10.1038/mi.2016.5. Epub 2016 Feb 17. Mucosal Immunol. 2016. PMID: 26883725 Free article.
Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow.
Siracusa F, McGrath MA, Maschmeyer P, Bardua M, Lehmann K, Heinz G, Durek P, Heinrich FF, Mashreghi MF, Chang HD, Tokoyoda K, Radbruch A. Siracusa F, et al. Among authors: lehmann k. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1334-1339. doi: 10.1073/pnas.1715618115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358404 Free PMC article.
Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+ EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ.
Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Maschmeyer P, et al. Among authors: lehmann k. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. Eur J Immunol. 2021. PMID: 33296081 Free article.
Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.
Riedel R, Addo R, Ferreira-Gomes M, Heinz GA, Heinrich F, Kummer J, Greiff V, Schulz D, Klaeden C, Cornelis R, Menzel U, Kröger S, Stervbo U, Köhler R, Haftmann C, Kühnel S, Lehmann K, Maschmeyer P, McGrath M, Naundorf S, Hahne S, Sercan-Alp Ö, Siracusa F, Stefanowski J, Weber M, Westendorf K, Zimmermann J, Hauser AE, Reddy ST, Durek P, Chang HD, Mashreghi MF, Radbruch A. Riedel R, et al. Among authors: lehmann k. Nat Commun. 2020 May 22;11(1):2570. doi: 10.1038/s41467-020-16464-6. Nat Commun. 2020. PMID: 32444631 Free PMC article.
Nuclear factor of activated T cells regulates the expression of interleukin-4 in Th2 cells in an all-or-none fashion.
Köck J, Kreher S, Lehmann K, Riedel R, Bardua M, Lischke T, Jargosch M, Haftmann C, Bendfeldt H, Hatam F, Mashreghi MF, Baumgrass R, Radbruch A, Chang HD. Köck J, et al. Among authors: lehmann k. J Biol Chem. 2014 Sep 26;289(39):26752-26761. doi: 10.1074/jbc.M114.587865. Epub 2014 Jul 17. J Biol Chem. 2014. PMID: 25037220 Free PMC article.
1,103 results