Lei L - Search Results

1

The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine.

Rupasinghe S, Schuler MA, Kagawa N, Yuan H, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC. Rupasinghe S, et al. Among authors: lei l. FEBS Lett. 2006 Nov 27;580(27):6338-42. doi: 10.1016/j.febslet.2006.10.043. Epub 2006 Oct 30. FEBS Lett. 2006. PMID: 17092500 Free article.

2

Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes.

Moody SC, Zhao B, Lei L, Nelson DR, Mullins JG, Waterman MR, Kelly SL, Lamb DC. Moody SC, et al. Among authors: lei l. FEBS J. 2012 May;279(9):1640-9. doi: 10.1111/j.1742-4658.2011.08447.x. Epub 2012 Jan 27. FEBS J. 2012. PMID: 22151149 Free article.

3

Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2.

Zhao B, Guengerich FP, Bellamine A, Lamb DC, Izumikawa M, Lei L, Podust LM, Sundaramoorthy M, Kalaitzis JA, Reddy LM, Kelly SL, Moore BS, Stec D, Voehler M, Falck JR, Shimada T, Waterman MR. Zhao B, et al. Among authors: lei l. J Biol Chem. 2005 Mar 25;280(12):11599-607. doi: 10.1074/jbc.M410933200. Epub 2005 Jan 19. J Biol Chem. 2005. PMID: 15659395 Free article.

4

Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2).

Chun YJ, Shimada T, Sanchez-Ponce R, Martin MV, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC, Guengerich FP. Chun YJ, et al. Among authors: lei l. J Biol Chem. 2007 Jun 15;282(24):17486-500. doi: 10.1074/jbc.M700863200. Epub 2007 Apr 19. J Biol Chem. 2007. PMID: 17446171 Free article.

5

Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.

Zhao B, Lamb DC, Lei L, Kelly SL, Yuan H, Hachey DL, Waterman MR. Zhao B, et al. Among authors: lei l. Biochemistry. 2007 Jul 31;46(30):8725-33. doi: 10.1021/bi7006959. Epub 2007 Jul 6. Biochemistry. 2007. PMID: 17614370

6

Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2).

Zhao B, Lin X, Lei L, Lamb DC, Kelly SL, Waterman MR, Cane DE. Zhao B, et al. Among authors: lei l. J Biol Chem. 2008 Mar 28;283(13):8183-9. doi: 10.1074/jbc.M710421200. Epub 2008 Jan 30. J Biol Chem. 2008. PMID: 18234666 Free PMC article.

7

The first virally encoded cytochrome p450.

Lamb DC, Lei L, Warrilow AG, Lepesheva GI, Mullins JG, Waterman MR, Kelly SL. Lamb DC, et al. Among authors: lei l. J Virol. 2009 Aug;83(16):8266-9. doi: 10.1128/JVI.00289-09. Epub 2009 Jun 10. J Virol. 2009. PMID: 19515774 Free PMC article.

8

Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.

Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR. Zhao B, et al. Among authors: lei l. J Biol Chem. 2009 Dec 25;284(52):36711-36719. doi: 10.1074/jbc.M109.064683. Epub 2009 Oct 26. J Biol Chem. 2009. PMID: 19858213 Free PMC article.

9

Structural analysis of cytochrome P450 105N1 involved in the biosynthesis of the zincophore, coelibactin.

Zhao B, Moody SC, Hider RC, Lei L, Kelly SL, Waterman MR, Lamb DC. Zhao B, et al. Among authors: lei l. Int J Mol Sci. 2012;13(7):8500-8513. doi: 10.3390/ijms13078500. Epub 2012 Jun 1. Int J Mol Sci. 2012. PMID: 22942716 Free PMC article.

10

Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2).

Lei L, Waterman MR, Fulco AJ, Kelly SL, Lamb DC. Lei L, et al. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):494-9. doi: 10.1073/pnas.2435922100. Epub 2004 Jan 2. Proc Natl Acad Sci U S A. 2004. PMID: 14704268 Free PMC article.

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