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Glucotoxicity and beta-cell failure in type 2 diabetes mellitus.
Kaiser N, Leibowitz G, Nesher R. Kaiser N, et al. Among authors: leibowitz g. J Pediatr Endocrinol Metab. 2003 Jan;16(1):5-22. doi: 10.1515/jpem.2003.16.1.5. J Pediatr Endocrinol Metab. 2003. PMID: 12585335 Review.
Reproducibility of glucose measurements using the glucose sensor.
Metzger M, Leibowitz G, Wainstein J, Glaser B, Raz I. Metzger M, et al. Among authors: leibowitz g. Diabetes Care. 2002 Jul;25(7):1185-91. doi: 10.2337/diacare.25.7.1185. Diabetes Care. 2002. PMID: 12087017
Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure.
Leibowitz G, Uçkaya G, Oprescu AI, Cerasi E, Gross DJ, Kaiser N. Leibowitz G, et al. Endocrinology. 2002 Sep;143(9):3214-20. doi: 10.1210/en.2002-220174. Endocrinology. 2002. PMID: 12193532
Insulin does not mediate glucose stimulation of proinsulin biosynthesis.
Leibowitz G, Oprescu AI, Uçkaya G, Gross DJ, Cerasi E, Kaiser N. Leibowitz G, et al. Diabetes. 2003 Apr;52(4):998-1003. doi: 10.2337/diabetes.52.4.998. Diabetes. 2003. PMID: 12663472
Psammomys obesus, a model for environment-gene interactions in type 2 diabetes.
Kaiser N, Nesher R, Donath MY, Fraenkel M, Behar V, Magnan C, Ktorza A, Cerasi E, Leibowitz G. Kaiser N, et al. Among authors: leibowitz g. Diabetes. 2005 Dec;54 Suppl 2:S137-44. doi: 10.2337/diabetes.54.suppl_2.s137. Diabetes. 2005. PMID: 16306331 Review.
Regulation of insulin secretion and proinsulin biosynthesis by succinate.
Attali V, Parnes M, Ariav Y, Cerasi E, Kaiser N, Leibowitz G. Attali V, et al. Among authors: leibowitz g. Endocrinology. 2006 Nov;147(11):5110-8. doi: 10.1210/en.2006-0496. Epub 2006 Aug 17. Endocrinology. 2006. PMID: 16916949
Inhibition of the NADPH-consuming enzyme neuronal nitric oxide synthase (nNOS) with l-N(G)-nitro-l-arginine methyl ester or with N(G)-monomethyl-l-arginine(G) doubled succinate-stimulated insulin secretion in rat islets, suggesting that succinate- and nNOS-de …
Inhibition of the NADPH-consuming enzyme neuronal nitric oxide synthase (nNOS) with l-N(G)-nitro-l-arginine methyl ester or with N( …
In-hospital treatment of hyperglycemia: effects of intensified subcutaneous insulin treatment.
Elinav H, Wolf Z, Szalat A, Bdolah-Abram T, Glaser B, Raz I, Leibowitz G. Elinav H, et al. Among authors: leibowitz g. Curr Med Res Opin. 2007 Apr;23(4):757-65. doi: 10.1185/030079907x178748. Curr Med Res Opin. 2007. PMID: 17407632 Clinical Trial.
Diabetes and the heart: could the diabetic myocardium be protected by preconditioning?
Vinokur V, Leibowitz G, Grinberg L, Eliashar R, Berenshtein E, Chevion M. Vinokur V, et al. Among authors: leibowitz g. Redox Rep. 2007;12(6):246-56. doi: 10.1179/135100007X239289. Redox Rep. 2007. PMID: 17961296 Review.
mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.
Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G. Fraenkel M, et al. Among authors: leibowitz g. Diabetes. 2008 Apr;57(4):945-57. doi: 10.2337/db07-0922. Epub 2008 Jan 3. Diabetes. 2008. PMID: 18174523
Scanning electron microscopic analysis of intramyocellular lipid droplets in an animal model of type 2 diabetes.
Fraenkel M, Weiss R, Leizerman I, Anaby D, Golomb E, Leibowitz G, Kaiser N. Fraenkel M, et al. Among authors: leibowitz g. Obesity (Silver Spring). 2008 Mar;16(3):695-9. doi: 10.1038/oby.2007.105. Epub 2008 Jan 17. Obesity (Silver Spring). 2008. PMID: 18239599
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