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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
König J, Nies AT, Cui Y, Leier I, Keppler D. König J, et al. Among authors: leier i. Biochim Biophys Acta. 1999 Dec 6;1461(2):377-94. doi: 10.1016/s0005-2736(99)00169-8. Biochim Biophys Acta. 1999. PMID: 10581368 Free article. Review.
Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate.
Bode KA, Donner MG, Leier I, Keppler D. Bode KA, et al. Among authors: leier i. Biochem Pharmacol. 2002 Jul 1;64(1):151-8. doi: 10.1016/s0006-2952(02)01015-8. Biochem Pharmacol. 2002. PMID: 12106615
Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2.
Kamisako T, Leier I, Cui Y, König J, Buchholz U, Hummel-Eisenbeiss J, Keppler D. Kamisako T, et al. Among authors: leier i. Hepatology. 1999 Aug;30(2):485-90. doi: 10.1002/hep.510300220. Hepatology. 1999. PMID: 10421658
Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B.
Nies AT, Cantz T, Brom M, Leier I, Keppler D. Nies AT, et al. Among authors: leier i. Hepatology. 1998 Nov;28(5):1332-40. doi: 10.1002/hep.510280523. Hepatology. 1998. PMID: 9794919
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.
Jedlitschky G, Leier I, Buchholz U, Hummel-Eisenbeiss J, Burchell B, Keppler D. Jedlitschky G, et al. Among authors: leier i. Biochem J. 1997 Oct 1;327 ( Pt 1)(Pt 1):305-10. doi: 10.1042/bj3270305. Biochem J. 1997. PMID: 9355767 Free PMC article.
Identification of the biosynthetic leukotriene C4 export pump in murine mastocytoma cells as a homolog of the multidrug-resistance protein.
Leier I, Jedlitschky G, Büchler M, Buchholz U, Brom M, Keppler D. Leier I, et al. Eur J Biochem. 1996 Dec 1;242(2):201-5. doi: 10.1111/j.1432-1033.1996.0201r.x. Eur J Biochem. 1996. PMID: 8973633
A membrane glycoprotein of 190 kDa has been identified previously by photoaffinity labeling as a candidate for the ATP-dependent export pump for leukotriene C4 in mastocytoma cells [Leier, I., Jedlitschky, G., Buchholz, U. & Keppler, D. (1994) Eur. ...
A membrane glycoprotein of 190 kDa has been identified previously by photoaffinity labeling as a candidate for the ATP-dependent export pump …
Identification of the multidrug-resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes.
Pulaski L, Jedlitschky G, Leier I, Buchholz U, Keppler D. Pulaski L, et al. Among authors: leier i. Eur J Biochem. 1996 Oct 15;241(2):644-8. doi: 10.1111/j.1432-1033.1996.00644.x. Eur J Biochem. 1996. PMID: 8917467
The function of the multidrug resistance proteins (MRP and cMRP) in drug conjugate transport and hepatobiliary excretion.
Keppler D, Leier I, Jedlitschky G, Mayer R, Büchler M. Keppler D, et al. Among authors: leier i. Adv Enzyme Regul. 1996;36:17-29. doi: 10.1016/0065-2571(95)00011-9. Adv Enzyme Regul. 1996. PMID: 8869738
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump.
Leier I, Jedlitschky G, Buchholz U, Center M, Cole SP, Deeley RG, Keppler D. Leier I, et al. Biochem J. 1996 Mar 1;314 ( Pt 2)(Pt 2):433-7. doi: 10.1042/bj3140433. Biochem J. 1996. PMID: 8670053 Free PMC article.
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.
Jedlitschky G, Leier I, Buchholz U, Barnouin K, Kurz G, Keppler D. Jedlitschky G, et al. Among authors: leier i. Cancer Res. 1996 Mar 1;56(5):988-94. Cancer Res. 1996. PMID: 8640791
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