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Development of 1,4-benzodiazepine cholecystokinin type B antagonists.
Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Garsky VM, Gilbert KF, Leighton JL, Carson KL, Mellin EC, et al. Bock MG, et al. Among authors: leighton jl. J Med Chem. 1993 Dec 24;36(26):4276-92. doi: 10.1021/jm00078a018. J Med Chem. 1993. PMID: 8277510
Orally active, nonpeptide oxytocin antagonists.
Evans BE, Leighton JL, Rittle KE, Gilbert KF, Lundell GF, Gould NP, Hobbs DW, DiPardo RM, Veber DF, Pettibone DJ, et al. Evans BE, et al. Among authors: leighton jl. J Med Chem. 1992 Oct 16;35(21):3919-27. doi: 10.1021/jm00099a020. J Med Chem. 1992. PMID: 1331449
Nanomolar-affinity, non-peptide oxytocin receptor antagonists.
Evans BE, Lundell GF, Gilbert KF, Bock MG, Rittle KE, Carroll LA, Williams PD, Pawluczyk JM, Leighton JL, Young MB, et al. Evans BE, et al. Among authors: leighton jl. J Med Chem. 1993 Dec 10;36(25):3993-4005. doi: 10.1021/jm00077a002. J Med Chem. 1993. PMID: 8258821
Efficient asymmetric synthesis of (+)-SCH 351448.
Bolshakov S, Leighton JL. Bolshakov S, et al. Among authors: leighton jl. Org Lett. 2005 Aug 18;7(17):3809-12. doi: 10.1021/ol0515006. Org Lett. 2005. PMID: 16092881 Free PMC article.
An efficient asymmetric synthesis of manzacidin C.
Tran K, Lombardi PJ, Leighton JL. Tran K, et al. Among authors: leighton jl. Org Lett. 2008 Jul 17;10(14):3165-7. doi: 10.1021/ol8011869. Epub 2008 Jun 24. Org Lett. 2008. PMID: 18572947
72 results